Peritoneal surface malignancies, also referred to as peritoneal metastases (PM), are often a late-stage development of cancers originating from any intra-abdominal organ that has spread to the peritoneal cavity. Although rare, it can also originate from the peritoneum. Prognosis for PM is poor and patients frequently suffer from local compressive symptoms leading to intestinal obstruction and cachexia. Cure may be feasible for a highly selected group of patients via cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. However, majority of patients are not suitable for the procedure and PM remains a difficult disease to treat.
There remains an urgent need to pursue diagnostic and therapeutic advances for PM through translational research. This research topic seeks to consolidate the expanding knowledge on translational research in the field of PM to provide insights to the development of novel diagnostic and therapeutic options for patients with PM.
The scope of this Research Topic is translational research with a focus on improving the diagnosis and therapeutic options in the field of PM. High quality Original Research articles, Systematic Reviews, Narrative Reviews, Mini Reviews, and Brief Research Reports that discuss on any aspect of translational research are welcome.
Important Note: Manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) will not be accepted in any of the sections of Frontiers in Oncology.
Peritoneal surface malignancies, also referred to as peritoneal metastases (PM), are often a late-stage development of cancers originating from any intra-abdominal organ that has spread to the peritoneal cavity. Although rare, it can also originate from the peritoneum. Prognosis for PM is poor and patients frequently suffer from local compressive symptoms leading to intestinal obstruction and cachexia. Cure may be feasible for a highly selected group of patients via cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. However, majority of patients are not suitable for the procedure and PM remains a difficult disease to treat.
There remains an urgent need to pursue diagnostic and therapeutic advances for PM through translational research. This research topic seeks to consolidate the expanding knowledge on translational research in the field of PM to provide insights to the development of novel diagnostic and therapeutic options for patients with PM.
The scope of this Research Topic is translational research with a focus on improving the diagnosis and therapeutic options in the field of PM. High quality Original Research articles, Systematic Reviews, Narrative Reviews, Mini Reviews, and Brief Research Reports that discuss on any aspect of translational research are welcome.
Important Note: Manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) will not be accepted in any of the sections of Frontiers in Oncology.