Pathophysiological alteration in the gut microbiota has been linked with the development and maintenance of non-communicable diseases, such as obesity, cancer, type 2 diabetes mellitus, cardiovascular diseases, and metabolic syndrome. There has been increasing evidence that microorganisms with claimed probiotic properties can exert benefits for human health in different age groups by modulating action on host metabolism, physiology, nutrition, and immune functions. Several probiotic strains have been considered safe and commercially available for human use through delivery by foods, beverages, and supplements. There has also been encouraging clinical evidence that some probiotic strains effectively manage and prevent a variety of metabolic disorders and illnesses in humans, characterizing probiotics as promising innovative therapeutic options for their treatment.
Although several studies have reported that probiotic microorganisms with claimed probiotics exert host health benefits, there are current gaps to optimize the use of probiotics for research nutrition and health that need to be approached. These have included understanding the mechanisms of how probiotics can affect different biochemical and physiological functions and optimum dose, frequency, and duration of treatment for different probiotic strains. Additionally, some species-level effects such as enzymatic activity, bile salt metabolism, neutralization of carcinogen, and vitamin synthesis; or rare strain-specific effects such as the production of specific bioactive, and neurological, immunological, and endocrinological effects have been little explored in studies with probiotics.
This Research Topic aims to join efforts to comprehend the effects of traditional and emerging probiotic microorganisms on the prevention and treatment of non-communicable disorders and illnesses. In particular, we are interested in the cellular and molecular mechanisms involved in the relationship between microorganisms with probiotic properties and the host health and disease conditions. Significant knowledge of probiotics microorganisms in food and nutrition science and perspectives about probiotics for human nutrition are also welcome. Original Research, Review and Perspective articles are encouraged. The general topics covered in this Research Topic are:
• The role of probiotics in human health such as metabolic and inflammatory diseases.
• The role of probiotics in maternal and child nutrition.
• The role of probiotics in elderly nutrition.
• Molecular mechanisms and cellular functions of the action of probiotics in health and nutritional disease.
• New probiotic microorganisms in food and nutrition science.
Pathophysiological alteration in the gut microbiota has been linked with the development and maintenance of non-communicable diseases, such as obesity, cancer, type 2 diabetes mellitus, cardiovascular diseases, and metabolic syndrome. There has been increasing evidence that microorganisms with claimed probiotic properties can exert benefits for human health in different age groups by modulating action on host metabolism, physiology, nutrition, and immune functions. Several probiotic strains have been considered safe and commercially available for human use through delivery by foods, beverages, and supplements. There has also been encouraging clinical evidence that some probiotic strains effectively manage and prevent a variety of metabolic disorders and illnesses in humans, characterizing probiotics as promising innovative therapeutic options for their treatment.
Although several studies have reported that probiotic microorganisms with claimed probiotics exert host health benefits, there are current gaps to optimize the use of probiotics for research nutrition and health that need to be approached. These have included understanding the mechanisms of how probiotics can affect different biochemical and physiological functions and optimum dose, frequency, and duration of treatment for different probiotic strains. Additionally, some species-level effects such as enzymatic activity, bile salt metabolism, neutralization of carcinogen, and vitamin synthesis; or rare strain-specific effects such as the production of specific bioactive, and neurological, immunological, and endocrinological effects have been little explored in studies with probiotics.
This Research Topic aims to join efforts to comprehend the effects of traditional and emerging probiotic microorganisms on the prevention and treatment of non-communicable disorders and illnesses. In particular, we are interested in the cellular and molecular mechanisms involved in the relationship between microorganisms with probiotic properties and the host health and disease conditions. Significant knowledge of probiotics microorganisms in food and nutrition science and perspectives about probiotics for human nutrition are also welcome. Original Research, Review and Perspective articles are encouraged. The general topics covered in this Research Topic are:
• The role of probiotics in human health such as metabolic and inflammatory diseases.
• The role of probiotics in maternal and child nutrition.
• The role of probiotics in elderly nutrition.
• Molecular mechanisms and cellular functions of the action of probiotics in health and nutritional disease.
• New probiotic microorganisms in food and nutrition science.