Benzodiazepine Addiction: From Lab to Street

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Editorial

22 September 2023

Editorial: Benzodiazepine addiction: from lab to street

Lais F. Berro

,

Thiago M. Fidalgo

,

James K. Rowlett

and

Vitor S. Tardelli

3,482 views

2 citations

Editors

4

Lais F Berro

University of Mississippi Medical Center

Thiago Marques Fidalgo

Federal University of São Paulo

James K. Rowlett

University of Mississippi Medical Center

Vitor Tardelli

Centre for Addiction and Mental Health, Dalla Lana School of Public Health, University of Toronto

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About

Benzodiazepine-type drugs (benzodiazepines and newer non-benzodiazepines, such as “Z drugs”) are important therapeutic tools in psychiatric medicine, being among the most highly prescribed psychiatric medications. Despite their clinical usefulness, benzodiazepines also induce several unwanted side effects, including abuse and dependence. In fact, the misuse and abuse of benzodiazepines have increased dramatically in recent years, with overdose deaths due to the combination of benzodiazepines and opioids reaching an all-time high, emphasizing that benzodiazepine abuse is cause for concern. Critically, no approved and broadly effective pharmacotherapy exists for the treatment of benzodiazepine misuse/use disorder.

The aim of this Research Topic is to highlight novel research examining factors related to the misuse, abuse, and dependence associated with benzodiazepine-type drugs.

Areas covered in this Research Topic may include, but are not limited to:
• Pre-clinical research investigating factors (e.g. genetic, environmental, neurobiological, pharmacological) associated with benzodiazepine use/misuse/use disorder;

• Translational studies aimed at identifying mechanisms and/or potential therapeutic strategies for benzodiazepine addiction;

• Studies examining sex differences in benzodiazepine use and abuse;

• Investigation of interactions between therapeutic and abuse-related effects of benzodiazepine-type drugs;

• Clinical and epidemiological studies reporting trends in the prevalence of benzodiazepine addiction and/or identifying determinants and related comorbidities of this disease;

• Review articles summarizing available research on benzodiazepine use disorder.

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Editors

Lais F Berro

University of Mississippi Medical Center

Thiago Marques Fidalgo

Federal University of São Paulo

James K. Rowlett

University of Mississippi Medical Center

Vitor Tardelli

Centre for Addiction and Mental Health, Dalla Lana School of Public Health, University of Toronto

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51,324 Total views

36,742 Article views

13,765 Article downloads

817 Topic views

Published In

Frontiers in Psychiatry

Addictive Disorders

Frontiers in Medicine

Family Medicine and Primary Care

Frontiers in Public Health

Family Medicine and Primary Care

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With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

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