Zoonoses refer to diseases or infections naturally transmissible from animals to humans, either through a person’s direct exposure to animals or by consuming food of animal origin. Zoonotic diseases have dated for thousands of years when humans captured and domesticated wild animals for several benefits. During the human era, zoonotic bacteria have been responsible for numerous harmful diseases causing millions of deaths, e.g., plague, caused by Yersinia pestis. Today, despite the development of healthcare systems and improved animal farming management systems, zoonotic bacteria still cause significant morbidity and mortality worldwide.
Antibiotics have long been used in the veterinary field to treat or prevent infections and promote growth. Growing evidence suggests that global use and abuse use of antibiotics has led to the development and dissemination of antimicrobial resistant bacteria. Although many antibiotics now have restricted use on animal farms, the occurrence of resistance to critical antimicrobials such as quinolones, 3rd and 4th generation of cephalosporins, carbapenems, and polymyxin keeps growing. Hence, there is an urgent need to understand the mechanisms behind the development and quick spread of antimicrobial resistant bacteria. In addition, we need to boost research for the development of non-antibiotic approaches to tackle the emergence of MDR zoonotic bacteria.
Overall, the main goal of this Research Topic is to analyze the genomic evolution of the emerging and re-emerging zoonotic bacteria, to gather and boost research on the mechanisms behind antimicrobial resistance, virulence, and pathogenicity of zoonotic bacteria as well as to create a debate on preventing strategies able to tackle the emergence of multidrug and virulent zoonotic bacteria.
We enthusiastically welcome researchers to submit their valuable reports, in the form of Original Research Articles, Review Articles, Brief Research Reports, Case Reports, Perspective Articles, Methods, and Opinions. The potential themes covered by this Research Topic, but not exclusively limited to, are:
- Antimicrobial resistance, virulence, and pathogenicity mechanisms of zoonotic bacteria,
- Pathogenicity assessment of emerging and reemerging zoonotic bacteria,
- Development of accurate typing methods to track the dissemination of zoonotic bacteria,
- Phylogenomic analysis and evolution of emerging and reemerging zoonotic bacteria,
- Whole genome sequencing and genomic investigation of zoonotic bacteria,
- Development of sustainable strategies to tackle the emergence of zoonotic bacteria.
Zoonoses refer to diseases or infections naturally transmissible from animals to humans, either through a person’s direct exposure to animals or by consuming food of animal origin. Zoonotic diseases have dated for thousands of years when humans captured and domesticated wild animals for several benefits. During the human era, zoonotic bacteria have been responsible for numerous harmful diseases causing millions of deaths, e.g., plague, caused by Yersinia pestis. Today, despite the development of healthcare systems and improved animal farming management systems, zoonotic bacteria still cause significant morbidity and mortality worldwide.
Antibiotics have long been used in the veterinary field to treat or prevent infections and promote growth. Growing evidence suggests that global use and abuse use of antibiotics has led to the development and dissemination of antimicrobial resistant bacteria. Although many antibiotics now have restricted use on animal farms, the occurrence of resistance to critical antimicrobials such as quinolones, 3rd and 4th generation of cephalosporins, carbapenems, and polymyxin keeps growing. Hence, there is an urgent need to understand the mechanisms behind the development and quick spread of antimicrobial resistant bacteria. In addition, we need to boost research for the development of non-antibiotic approaches to tackle the emergence of MDR zoonotic bacteria.
Overall, the main goal of this Research Topic is to analyze the genomic evolution of the emerging and re-emerging zoonotic bacteria, to gather and boost research on the mechanisms behind antimicrobial resistance, virulence, and pathogenicity of zoonotic bacteria as well as to create a debate on preventing strategies able to tackle the emergence of multidrug and virulent zoonotic bacteria.
We enthusiastically welcome researchers to submit their valuable reports, in the form of Original Research Articles, Review Articles, Brief Research Reports, Case Reports, Perspective Articles, Methods, and Opinions. The potential themes covered by this Research Topic, but not exclusively limited to, are:
- Antimicrobial resistance, virulence, and pathogenicity mechanisms of zoonotic bacteria,
- Pathogenicity assessment of emerging and reemerging zoonotic bacteria,
- Development of accurate typing methods to track the dissemination of zoonotic bacteria,
- Phylogenomic analysis and evolution of emerging and reemerging zoonotic bacteria,
- Whole genome sequencing and genomic investigation of zoonotic bacteria,
- Development of sustainable strategies to tackle the emergence of zoonotic bacteria.