UN World Autism Awareness Day took place on the 2nd April. This day is designated to promote international awareness for Autistic Spectrum Disorders (ASDs). Over the past decade, major progress has been made towards removing inequalities for people with autism . However, in 2020, as the COVID-19 pandemic spread across the globe, a majority of countries announced lockdowns, impacting more than 90% of people worldwide. Many people with autism have been especially hard hit and studies show that they have been disproportionately affected by disruptions to routines, as well as services and supports that they rely on. This Research Topic will focus on New Insights into the Molecular Mechanisms of Autistic Spectrum Disorders
ASD has been known as a lifelong neurodevelopmental disorder for many decades, which has been shown to have profound effects on intellectual ability and psychological functioning as well as general ability. This Research Topic aims to unravel new insights into the molecular mechanisms involved in Autistic Spectrum Disorders.
Molecular mechanisms and pathways underlying autism have been extensively studied over the decades. These also include neuroanatomical studies which have been able to report on macrocephaly and abnormal neuronal connectivity in autistic individuals. Furthermore, genetics studies using mouse models and twin studies have implicated a variety of neuronal proteins in the development of ASD. More recently, defects in a number of synaptic proteins have been suggested to be involved in the development of ASD due to alterations in synaptic structure/function and neural circuits, suggesting that “synaptopathy” is an important component of ASD.
The aim of this Research Topic is to feature a collection of articles on altered molecular pathways and mechanisms associated with ASD. Some topics of interest are (but not limited to):
-Neuroanatomical Abnormalities in Autism
-Growth factors and neurotrophic factors associated with ASD
-Defective transcription factors affecting diverse neuronal functions
-Excitatory and Inhibitory Imbalance in ASD
-Disrupted synaptic signaling
-Neuroimmune Responses in Autism
-Epigenetic rewiring
-Information processing and somatosensory pathways
-Genetic insights into Autism Spectrum Disorders
-Role of SNPs in Autism Spectrum Disorders
UN World Autism Awareness Day took place on the 2nd April. This day is designated to promote international awareness for Autistic Spectrum Disorders (ASDs). Over the past decade, major progress has been made towards removing inequalities for people with autism . However, in 2020, as the COVID-19 pandemic spread across the globe, a majority of countries announced lockdowns, impacting more than 90% of people worldwide. Many people with autism have been especially hard hit and studies show that they have been disproportionately affected by disruptions to routines, as well as services and supports that they rely on. This Research Topic will focus on New Insights into the Molecular Mechanisms of Autistic Spectrum Disorders
ASD has been known as a lifelong neurodevelopmental disorder for many decades, which has been shown to have profound effects on intellectual ability and psychological functioning as well as general ability. This Research Topic aims to unravel new insights into the molecular mechanisms involved in Autistic Spectrum Disorders.
Molecular mechanisms and pathways underlying autism have been extensively studied over the decades. These also include neuroanatomical studies which have been able to report on macrocephaly and abnormal neuronal connectivity in autistic individuals. Furthermore, genetics studies using mouse models and twin studies have implicated a variety of neuronal proteins in the development of ASD. More recently, defects in a number of synaptic proteins have been suggested to be involved in the development of ASD due to alterations in synaptic structure/function and neural circuits, suggesting that “synaptopathy” is an important component of ASD.
The aim of this Research Topic is to feature a collection of articles on altered molecular pathways and mechanisms associated with ASD. Some topics of interest are (but not limited to):
-Neuroanatomical Abnormalities in Autism
-Growth factors and neurotrophic factors associated with ASD
-Defective transcription factors affecting diverse neuronal functions
-Excitatory and Inhibitory Imbalance in ASD
-Disrupted synaptic signaling
-Neuroimmune Responses in Autism
-Epigenetic rewiring
-Information processing and somatosensory pathways
-Genetic insights into Autism Spectrum Disorders
-Role of SNPs in Autism Spectrum Disorders
