Technological advances have contributed to a rise in the detection and understanding of human diseases. This has been especially true for diseases associated with the nervous system. This improved understanding of disease pathogenesis has led to increased efforts in the discovery of disease-modifying therapeutics. Numerous triggers, including trauma, hypoxia, and other various forms of cellular stress, epigenetic factors, and metabolic diseases/imbalances have been intimately associated with neurodegenerative diseases. The literature is strewn with molecular mechanisms and pathways that define or explain how various triggers can produce pathognomonic features associated with neurodegenerative diseases. The challenge we now face is to combine these findings and provide holistic therapeutic approaches. Advances in disease detection mechanisms will hopefully enable an early diagnosis. There is therefore an urgent need for treatments that will delay the onset of these diseases as well as those that will slow their progression.
The aim of this research topic is to provide a repository for articles that address but are not limited to the following areas of interest:
i) original research articles describing therapeutic approaches to both common as well as less prevalent neurodegenerative diseases
ii) original research articles describing novel or emerging therapeutic approaches to neurodegenerative diseases
iii) original research articles that describe therapeutic approaches targeting individual pathways that are common to multiple neurodegenerative diseases
iv) review articles that summarize therapeutic approaches to neurodegenerative diseases
v) perspectives that highlight possible avenues to therapeutic approaches targeting neurodegenerative diseases.
Manuscripts could also be based on methodologies, hypotheses and theories, mini-reviews or reviews, clinical trials, and technological reports.
Technological advances have contributed to a rise in the detection and understanding of human diseases. This has been especially true for diseases associated with the nervous system. This improved understanding of disease pathogenesis has led to increased efforts in the discovery of disease-modifying therapeutics. Numerous triggers, including trauma, hypoxia, and other various forms of cellular stress, epigenetic factors, and metabolic diseases/imbalances have been intimately associated with neurodegenerative diseases. The literature is strewn with molecular mechanisms and pathways that define or explain how various triggers can produce pathognomonic features associated with neurodegenerative diseases. The challenge we now face is to combine these findings and provide holistic therapeutic approaches. Advances in disease detection mechanisms will hopefully enable an early diagnosis. There is therefore an urgent need for treatments that will delay the onset of these diseases as well as those that will slow their progression.
The aim of this research topic is to provide a repository for articles that address but are not limited to the following areas of interest:
i) original research articles describing therapeutic approaches to both common as well as less prevalent neurodegenerative diseases
ii) original research articles describing novel or emerging therapeutic approaches to neurodegenerative diseases
iii) original research articles that describe therapeutic approaches targeting individual pathways that are common to multiple neurodegenerative diseases
iv) review articles that summarize therapeutic approaches to neurodegenerative diseases
v) perspectives that highlight possible avenues to therapeutic approaches targeting neurodegenerative diseases.
Manuscripts could also be based on methodologies, hypotheses and theories, mini-reviews or reviews, clinical trials, and technological reports.