The organism has certain requirements for various nutrients to maintain the energy supply, growth, and development of the body. Likewise, the growth, development, and function maintenance of the cells are also accompanied by the metabolism of nutrients. The organelles participate in the processes of nutrient metabolism, including energy synthesis, protein metabolism, sucrose metabolism, etc. Notably, the occurrence of nutritional and metabolic diseases caused by nutritional deficiencies and metabolism disorders exhibits close connections with organelle dysfunction. For instance, the dysfunctions of the endoplasmic reticulum and mitochondria are the main reasons for abnormal metabolic functions such as lipid metabolism and energy synthesis. Therefore, an in-depth study of the changes in organelle structure, function, and interaction network in animal nutrition and metabolic disorders, poisoning, and other diseases can further clarify the mechanism of the occurrence and development of nutrition and metabolic diseases and find relevant regulatory targets. This is of great significance for the prevention and clinical treatment of nutritional metabolic diseases.
This Research Topic contributes to providing publications regarding research on the relations between organelles dysfunction and nutrition and metabolism-related diseases. It also spotlights the underlying mechanisms of the dysfunction of organelles and their effects on nutrition and metabolism disorders. We welcome Mini-Reviews, full-length Reviews, and Original Research papers in the following subtopics:
• The effects of organelles dysfunction on nutrition and metabolism functions in animal diseases.
• The effects of abnormal organelles interactions on material metabolism in animal diseases.
• The molecular crosstalk between organelles in animal nutrition and metabolic diseases.
• The relationships between the differences of organelles genome and metabolic function in animal diseases.
• The regulatory mechanisms of endoplasmic reticulum, lysosome, Golgi apparatus, and mitochondria in animal nutrition and metabolism diseases.
• The relationship between the imbalance of nutrition and metabolism caused by animal poisoning and organelle interaction network.
The organism has certain requirements for various nutrients to maintain the energy supply, growth, and development of the body. Likewise, the growth, development, and function maintenance of the cells are also accompanied by the metabolism of nutrients. The organelles participate in the processes of nutrient metabolism, including energy synthesis, protein metabolism, sucrose metabolism, etc. Notably, the occurrence of nutritional and metabolic diseases caused by nutritional deficiencies and metabolism disorders exhibits close connections with organelle dysfunction. For instance, the dysfunctions of the endoplasmic reticulum and mitochondria are the main reasons for abnormal metabolic functions such as lipid metabolism and energy synthesis. Therefore, an in-depth study of the changes in organelle structure, function, and interaction network in animal nutrition and metabolic disorders, poisoning, and other diseases can further clarify the mechanism of the occurrence and development of nutrition and metabolic diseases and find relevant regulatory targets. This is of great significance for the prevention and clinical treatment of nutritional metabolic diseases.
This Research Topic contributes to providing publications regarding research on the relations between organelles dysfunction and nutrition and metabolism-related diseases. It also spotlights the underlying mechanisms of the dysfunction of organelles and their effects on nutrition and metabolism disorders. We welcome Mini-Reviews, full-length Reviews, and Original Research papers in the following subtopics:
• The effects of organelles dysfunction on nutrition and metabolism functions in animal diseases.
• The effects of abnormal organelles interactions on material metabolism in animal diseases.
• The molecular crosstalk between organelles in animal nutrition and metabolic diseases.
• The relationships between the differences of organelles genome and metabolic function in animal diseases.
• The regulatory mechanisms of endoplasmic reticulum, lysosome, Golgi apparatus, and mitochondria in animal nutrition and metabolism diseases.
• The relationship between the imbalance of nutrition and metabolism caused by animal poisoning and organelle interaction network.