Infectious diseases have afflicted the world for time immemorial. From chronic infections like tuberculosis, cytomegalovirus etc to acute infections like tetanus, COVID-19, infectious diseases remain a formidable threat to human and animal life. The rise of non-communicable diseases (NCDs) due to changing environment and lifestyles has further complicated the landscape of infectious diseases in the form of comorbidity and multimorbidity. Accurate diagnosis is crucial for effective management of all diseases, more so infectious diseases. Advancement in technology and understanding of the molecular basis of life offers promise for attaining accurate diagnosis in real-time.
The purpose of this Research Topic is to showcase the advances in diagnostic technology and how these technologies are resolving the diagnostic challenge of infectious diseases. While delayed diagnosis may not be fatal for chronic infections, the reverse is true for acute infections. Nevertheless, early diagnosis is crucial irrespective of type infection because the earlier the diagnosis the higher the chance of successful treatment and prevention of transmission. Advances in molecular biology, imaging (nuclear & non-nuclear) biosensors, data science and digital software engineering are stepping to solve the diagnostic challenge and provide diagnosis at- or near- point-of-care. This Research Topic provides a one-stop platform to highlight these advances both in development and/or in routine clinical use. The manuscripts will highlight the principles underlying the technologies and evidence to showcase applicability in targeted areas of implementation.
The topic discusses novel approaches to diagnose infectious diseases. This encompasses all advances in the field of infectious diagnosis, from enhanced phenotypic tests to molecular and digital diagnostics. Enhanced phenotypic tests include for example the SLIC that diagnoses antibiotic resistance in minutes for rapidly growing bacteria and hours for slow growers like Mycobacterium tuberculosis. Each showcased diagnostic technology should demonstrate the value added to diagnostic accuracy and time for clinical decision making. Manuscripts can be submitted in the following areas:
• Enhanced phenotypic diagnostics
• Molecular diagnostics including whole genome sequencing
• Imaging (from microscopy to PET CT scanners)
• Biosensor-based diagnostics
• Digital diagnostics
• Others e.g breath-based diagnostics
Infectious diseases have afflicted the world for time immemorial. From chronic infections like tuberculosis, cytomegalovirus etc to acute infections like tetanus, COVID-19, infectious diseases remain a formidable threat to human and animal life. The rise of non-communicable diseases (NCDs) due to changing environment and lifestyles has further complicated the landscape of infectious diseases in the form of comorbidity and multimorbidity. Accurate diagnosis is crucial for effective management of all diseases, more so infectious diseases. Advancement in technology and understanding of the molecular basis of life offers promise for attaining accurate diagnosis in real-time.
The purpose of this Research Topic is to showcase the advances in diagnostic technology and how these technologies are resolving the diagnostic challenge of infectious diseases. While delayed diagnosis may not be fatal for chronic infections, the reverse is true for acute infections. Nevertheless, early diagnosis is crucial irrespective of type infection because the earlier the diagnosis the higher the chance of successful treatment and prevention of transmission. Advances in molecular biology, imaging (nuclear & non-nuclear) biosensors, data science and digital software engineering are stepping to solve the diagnostic challenge and provide diagnosis at- or near- point-of-care. This Research Topic provides a one-stop platform to highlight these advances both in development and/or in routine clinical use. The manuscripts will highlight the principles underlying the technologies and evidence to showcase applicability in targeted areas of implementation.
The topic discusses novel approaches to diagnose infectious diseases. This encompasses all advances in the field of infectious diagnosis, from enhanced phenotypic tests to molecular and digital diagnostics. Enhanced phenotypic tests include for example the SLIC that diagnoses antibiotic resistance in minutes for rapidly growing bacteria and hours for slow growers like Mycobacterium tuberculosis. Each showcased diagnostic technology should demonstrate the value added to diagnostic accuracy and time for clinical decision making. Manuscripts can be submitted in the following areas:
• Enhanced phenotypic diagnostics
• Molecular diagnostics including whole genome sequencing
• Imaging (from microscopy to PET CT scanners)
• Biosensor-based diagnostics
• Digital diagnostics
• Others e.g breath-based diagnostics