The design of biomaterials that suit the native tissues is crucial for the development of implants, scaffolds, and hydrogels for bone and dental repair. However, synthetic biomaterials alone do not fully mimic the chemical and biological features of the native extracellular matrix. Therefore, researchers are focusing on favorable chemical and physiological properties in their development of biofunctional materials. Biofunctional materials incorporated with small molecules such as growth factors, peptides, cells, drugs, and genes can guide and promote new tissue formation during the restoration process. Coating of implants and biomedical devices with advantageous biofunctional material can foster biological activities to enhance the success of treatment for patients.
Biofunctional materials should recapitulate the functional and structural characteristics of the tissue being reconstructed. In the field of orthopedic and dental care, resilient and long-lasting regeneration of hard tissue is an important and essential requirement for biofunctional materials. Biofunctional materials for bone and tooth tissue engineering with bioactive properties promote tissue formation in tissue repair and regeneration. One of the recent advances in biofunctional materials is the inclusion of small biomolecules to functionalize polymers, nanoscale conjugative molecules, self-assembling molecules, and synthetic membranes. However, the translation of these biofunctional materials to the clinic is elusive because of the complicated host-biomaterial interactions. In addition, the lack of suitable pre-clinic models, the high cost of clinical trials, and the complicated regulatory pathways for commercialization are barriers to the development of new biofunctional materials. Collaboration of researchers, surgeons, and regulatory bodies can facilitate the development and use of new biofunctional materials for clinical care. In recent years, researchers of cellular biology, immunology, material science, and bioengineering have been working together to design and synthesize novel biofunctional materials for bone and tooth tissue engineering. The goal of this research topic is to encourage researchers to report their studies on the design and development of new biofunctional materials and their coatings for biomedical applications.
The proposed research topic “Biofunctional Materials and Coatings for Orthopedic and Dental Applications” emphasizes the new concepts, ideas, and advancing research progress on the design, development, and characterization of biofunctional materials, bioinspired material, and surface coatings for bone and tooth tissue engineering. This research topic welcomes the original research manuscripts, reviews, case reports, mini reviews from but not limited to the following themes.
• Biofunctional materials for bone and tooth tissue engineering
• Surface functionalization of scaffolds, hydrogels, and implants
• Biofunctional material coatings combating bacterial infections
• Biofunctional biomaterials for diagnostic and therapeutic uses
• Bioinspired materials and their composites for orthopedic and dental application
• Biofunctional inorganic materials for regenerative purposes
The design of biomaterials that suit the native tissues is crucial for the development of implants, scaffolds, and hydrogels for bone and dental repair. However, synthetic biomaterials alone do not fully mimic the chemical and biological features of the native extracellular matrix. Therefore, researchers are focusing on favorable chemical and physiological properties in their development of biofunctional materials. Biofunctional materials incorporated with small molecules such as growth factors, peptides, cells, drugs, and genes can guide and promote new tissue formation during the restoration process. Coating of implants and biomedical devices with advantageous biofunctional material can foster biological activities to enhance the success of treatment for patients.
Biofunctional materials should recapitulate the functional and structural characteristics of the tissue being reconstructed. In the field of orthopedic and dental care, resilient and long-lasting regeneration of hard tissue is an important and essential requirement for biofunctional materials. Biofunctional materials for bone and tooth tissue engineering with bioactive properties promote tissue formation in tissue repair and regeneration. One of the recent advances in biofunctional materials is the inclusion of small biomolecules to functionalize polymers, nanoscale conjugative molecules, self-assembling molecules, and synthetic membranes. However, the translation of these biofunctional materials to the clinic is elusive because of the complicated host-biomaterial interactions. In addition, the lack of suitable pre-clinic models, the high cost of clinical trials, and the complicated regulatory pathways for commercialization are barriers to the development of new biofunctional materials. Collaboration of researchers, surgeons, and regulatory bodies can facilitate the development and use of new biofunctional materials for clinical care. In recent years, researchers of cellular biology, immunology, material science, and bioengineering have been working together to design and synthesize novel biofunctional materials for bone and tooth tissue engineering. The goal of this research topic is to encourage researchers to report their studies on the design and development of new biofunctional materials and their coatings for biomedical applications.
The proposed research topic “Biofunctional Materials and Coatings for Orthopedic and Dental Applications” emphasizes the new concepts, ideas, and advancing research progress on the design, development, and characterization of biofunctional materials, bioinspired material, and surface coatings for bone and tooth tissue engineering. This research topic welcomes the original research manuscripts, reviews, case reports, mini reviews from but not limited to the following themes.
• Biofunctional materials for bone and tooth tissue engineering
• Surface functionalization of scaffolds, hydrogels, and implants
• Biofunctional material coatings combating bacterial infections
• Biofunctional biomaterials for diagnostic and therapeutic uses
• Bioinspired materials and their composites for orthopedic and dental application
• Biofunctional inorganic materials for regenerative purposes