Metabolic disease (MD) mainly refers to the abnormality of the body's material metabolism or energy metabolism and the metabolic disorder, which is usually a chronic disease with systemic abnormalities in the whole body. Most metabolic diseases have genetic factors, diet, toxins, infections, and other factors. Common clinical diseases such as metabolic disease caused by atherosclerosis, gout, diabetes and various complications, cancer, involving chronic respiratory diseases, digestion (oral, gastrointestinal), circulation (blood, lymph, body fluids), endocrine disorders, urinary (kidney), exercise (skeleton), neuropathy, reproductive (genital tract, polycystic ovary syndrome, etc.) and other chronic diseases of eight significant systems. Given that MD is now a considerable health problem casting a substantial burden on the public health system and caregivers, the prevention and treatment of MD have been eliciting powerful interests theoretically and practically. Most research mainly attempts to explore the pathogenesis, development process, pathological mechanism, treatment methods of MD, etc. Furthermore, cross-diseases such as metabolic syndrome and diabetic cardiomyopathy are gradually becoming the central subjects of MD research. The breakthrough in each field can provide more inspirable information for explaining the progression of MD and bring more hope for curing MD patients.
This Research Topic would like to discuss the following areas but not limited to:
(1) Based on modern medical biotechnology, explore the pathogenesis of MD such as atherosclerosis, metabolic syndrome, gout and polycystic ovarian syndrome, and identify new targets.
(2) According to evidence-based medicine theory, explore the safety, efficacy, and mechanism of novel molecule components with metabolic disease protective potential, such as antithrombus and cholesterol-lowering.
(3) Application of novel methods for metabolic disease in vivo and clinical studies.
(4) Assessment of efficacy and safety of Chinese patent medicines or functional components from TCM (or combined with Western medicine) in treating metabolic disease.
(5) Exploring new cross-over diseases such as metabolic syndrome and diabetic cardiomyopathy mechanisms.
Please note that Frontiers in Pharmacology - Experimental Pharmacology and Drug Discovery section does not accept for publication studies carried out with crude extracts or mixtures. Only the use of highly purified, chemically characterized compounds is acceptable.
This applies also to reviews, perspective, opinion.
This applies also to in silico studies on supposed mechanisms underlying supposed actions of crude extracts and/or mixtures.
Whenever a complex mixture is used, data with the single components of the mixture, in precisely defined dose/concentration, should be provided (and/or previously published)
Metabolic disease (MD) mainly refers to the abnormality of the body's material metabolism or energy metabolism and the metabolic disorder, which is usually a chronic disease with systemic abnormalities in the whole body. Most metabolic diseases have genetic factors, diet, toxins, infections, and other factors. Common clinical diseases such as metabolic disease caused by atherosclerosis, gout, diabetes and various complications, cancer, involving chronic respiratory diseases, digestion (oral, gastrointestinal), circulation (blood, lymph, body fluids), endocrine disorders, urinary (kidney), exercise (skeleton), neuropathy, reproductive (genital tract, polycystic ovary syndrome, etc.) and other chronic diseases of eight significant systems. Given that MD is now a considerable health problem casting a substantial burden on the public health system and caregivers, the prevention and treatment of MD have been eliciting powerful interests theoretically and practically. Most research mainly attempts to explore the pathogenesis, development process, pathological mechanism, treatment methods of MD, etc. Furthermore, cross-diseases such as metabolic syndrome and diabetic cardiomyopathy are gradually becoming the central subjects of MD research. The breakthrough in each field can provide more inspirable information for explaining the progression of MD and bring more hope for curing MD patients.
This Research Topic would like to discuss the following areas but not limited to:
(1) Based on modern medical biotechnology, explore the pathogenesis of MD such as atherosclerosis, metabolic syndrome, gout and polycystic ovarian syndrome, and identify new targets.
(2) According to evidence-based medicine theory, explore the safety, efficacy, and mechanism of novel molecule components with metabolic disease protective potential, such as antithrombus and cholesterol-lowering.
(3) Application of novel methods for metabolic disease in vivo and clinical studies.
(4) Assessment of efficacy and safety of Chinese patent medicines or functional components from TCM (or combined with Western medicine) in treating metabolic disease.
(5) Exploring new cross-over diseases such as metabolic syndrome and diabetic cardiomyopathy mechanisms.
Please note that Frontiers in Pharmacology - Experimental Pharmacology and Drug Discovery section does not accept for publication studies carried out with crude extracts or mixtures. Only the use of highly purified, chemically characterized compounds is acceptable.
This applies also to reviews, perspective, opinion.
This applies also to in silico studies on supposed mechanisms underlying supposed actions of crude extracts and/or mixtures.
Whenever a complex mixture is used, data with the single components of the mixture, in precisely defined dose/concentration, should be provided (and/or previously published)