Neonatal surgery is performed on babies shortly after they are born. Neonatal surgery is used to treat many different conditions such as:
• Anorectal malformations
• Pyloric stenosis
• diaphragmatic hernia
• Biliary atresia
• Congenital diaphragmatic hernia
• Esophageal atresia with or without tracheoesophageal fistula
• Gastroschisis
• Head and neck lesion/mass
• Hirschsprung’s disease
• Intestinal atresia/anomalies
• Lung lesions
• Necrotizing enterocolitis
• Omphalocele
• Tumour and oncology
• Short bowel syndrome
• Tracheoesophageal fistula
Despite decades of clinical and basic research advances, the outcomes of these conditions especially among preterm infants remain serious, and there are still unsolved clinical problems. Moreover, the psychosocial, family impact, and economic burden of these conditions are frequently overlooked in clinical studies. Thus, there is an urgent and pressing need for a deeper understanding of the pathophysiology and innovative therapeutic approaches for these diseases.
The goal of this Research Topic is to introduce a change in the paradigm of care of infants and children affected by these diseases. The experimental research can provide useful information on disease initiation and clinical research can develop novel precise treatment or management strategies. In addition, discoveries arising from the proposed research program can open the avenue to further research into (i) the usefulness of the above therapeutic maneuvers in children suffering from a variety of diseases, and (ii) its profound consequences to the children, their parents, family functioning, local community, and society at large. The impact of our research topic will be quantified clinically by the stringent criteria determined by randomized controlled trial guidelines. A further novelty is the consideration of psychosocial impacts of treatment by examining child and caregiver biopsychosocial outcomes including quality of life and general functioning, mental health, impact on the family, and service system-level outcomes including perceptions of care and economic costs.
The scope of this Research Topic is to highlight ongoing work done to address gaps in our knowledge of neonatal babies with surgical issues (or a surgical issue). We invite researchers to submit manuscripts of original clinical or experimental research, systematic reviews, meta-analyses, literature review, case reports, or guidelines which cover, but are not limited to, the following topics:
• Recent epidemiology of neonates with the surgical issue
• Outcomes of prenatal diagnosed structural anomalies based on multi-disciplinary principles
• Advances in the understanding of the pathophysiology of neonates with surgical issues
• Surgical outcomes in extra-low birth weight infants
• Risk stratification and/or prediction rules for neonates with surgical issues
• Newer biomarkers for diagnosis of neonates with surgical issues
• Novel clinical strategies for neonates with surgical issues
• Nutritional or microbiota-targeted therapies in neonates with surgical conditions
• Long-term complications and sequelae of neonates with surgical issues
Neonatal surgery is performed on babies shortly after they are born. Neonatal surgery is used to treat many different conditions such as:
• Anorectal malformations
• Pyloric stenosis
• diaphragmatic hernia
• Biliary atresia
• Congenital diaphragmatic hernia
• Esophageal atresia with or without tracheoesophageal fistula
• Gastroschisis
• Head and neck lesion/mass
• Hirschsprung’s disease
• Intestinal atresia/anomalies
• Lung lesions
• Necrotizing enterocolitis
• Omphalocele
• Tumour and oncology
• Short bowel syndrome
• Tracheoesophageal fistula
Despite decades of clinical and basic research advances, the outcomes of these conditions especially among preterm infants remain serious, and there are still unsolved clinical problems. Moreover, the psychosocial, family impact, and economic burden of these conditions are frequently overlooked in clinical studies. Thus, there is an urgent and pressing need for a deeper understanding of the pathophysiology and innovative therapeutic approaches for these diseases.
The goal of this Research Topic is to introduce a change in the paradigm of care of infants and children affected by these diseases. The experimental research can provide useful information on disease initiation and clinical research can develop novel precise treatment or management strategies. In addition, discoveries arising from the proposed research program can open the avenue to further research into (i) the usefulness of the above therapeutic maneuvers in children suffering from a variety of diseases, and (ii) its profound consequences to the children, their parents, family functioning, local community, and society at large. The impact of our research topic will be quantified clinically by the stringent criteria determined by randomized controlled trial guidelines. A further novelty is the consideration of psychosocial impacts of treatment by examining child and caregiver biopsychosocial outcomes including quality of life and general functioning, mental health, impact on the family, and service system-level outcomes including perceptions of care and economic costs.
The scope of this Research Topic is to highlight ongoing work done to address gaps in our knowledge of neonatal babies with surgical issues (or a surgical issue). We invite researchers to submit manuscripts of original clinical or experimental research, systematic reviews, meta-analyses, literature review, case reports, or guidelines which cover, but are not limited to, the following topics:
• Recent epidemiology of neonates with the surgical issue
• Outcomes of prenatal diagnosed structural anomalies based on multi-disciplinary principles
• Advances in the understanding of the pathophysiology of neonates with surgical issues
• Surgical outcomes in extra-low birth weight infants
• Risk stratification and/or prediction rules for neonates with surgical issues
• Newer biomarkers for diagnosis of neonates with surgical issues
• Novel clinical strategies for neonates with surgical issues
• Nutritional or microbiota-targeted therapies in neonates with surgical conditions
• Long-term complications and sequelae of neonates with surgical issues