Polysaccharides are important components of ubiquitous medicinal fungi and marine organisms. Fungal (medicinal herbal) polysaccharides, sulphated polysaccharides, namely fucoidan from seaweeds have been investigated over the past few decades for their specific activities. However, in addition to the current research status and prospects, it is necessary to focus on the molecular mechanisms of medicinal polysaccharides/fucoidan and comprehensively dissect their overall biological functions. Moreover, polysaccharides are used as drug delivery media. To further explore the applicability and increase the biological activities may provide the novel aspect of polysaccharides.
In this Research Topic, we explore studies focusing on the pharmacological effects (such as antitumor, immunomodulatory, anti-inflammatory activities, etc.) and the clinical applicability of fungal polysaccharides and fucoidan. Specifically, we further explore the potential molecular mechanism and utility of medicinal polysaccharides and expect that related studies could be correlated to translational medicine with applications related to the health food, and medical industries.
The goal of the Research Topic is to discuss recent pharmacological progress and clinical application of fungal polysaccharides and fucoidan and to dissect the underlying mechanisms. We expect to collect the studies relevant to polysaccharides and jointly bring advanced scientific progress to polysaccharide research.
Contributions for this Research Topic, both in form of Original Research and Review articles, cover all aspects of fungal polysaccharides and fucoidan. Especially, the Issue focuses on biological functions and action mechanisms, e.g. biological and chemical characterization of polysaccharides from fungi as well as fucoidan; development of the novel strategies for increasing pharmacological activity from fungi and marine organisms; identification of novel molecular mechanisms on fungal polysaccharides and fucoidan suppressed various diseases; application strategies of polysaccharides for pharmaceutical delivery.
We welcome Original Research and Reviews focusing on the following subtopics, but not limited to:
1. Biological pharmacological effects of polysaccharides from fungi as well as fucoidan
2. Isolation, chemical, and structural characterization of novel polysaccharides from fungi as well as fucoidan from seaweed.
3. The application of polysaccharides on pharmaceutical delivery
4. The method for increasing the biological activities of polysaccharides from fungi
5. Clinical research of fungal polysaccharides and fucoidan.
Please note: Frontiers in Experimental Pharmacology and Drug Discovery does not accept publication studies carried out with crude extracts or mixtures. Only the use of highly purified, chemically characterized compounds is acceptable. In vivo systemic effects following oral polysaccharide administration cannot be claimed unless validated by analytical assessment of the plasma concentration of the specific polysaccharide or its monosaccharide constituents.
Polysaccharides are important components of ubiquitous medicinal fungi and marine organisms. Fungal (medicinal herbal) polysaccharides, sulphated polysaccharides, namely fucoidan from seaweeds have been investigated over the past few decades for their specific activities. However, in addition to the current research status and prospects, it is necessary to focus on the molecular mechanisms of medicinal polysaccharides/fucoidan and comprehensively dissect their overall biological functions. Moreover, polysaccharides are used as drug delivery media. To further explore the applicability and increase the biological activities may provide the novel aspect of polysaccharides.
In this Research Topic, we explore studies focusing on the pharmacological effects (such as antitumor, immunomodulatory, anti-inflammatory activities, etc.) and the clinical applicability of fungal polysaccharides and fucoidan. Specifically, we further explore the potential molecular mechanism and utility of medicinal polysaccharides and expect that related studies could be correlated to translational medicine with applications related to the health food, and medical industries.
The goal of the Research Topic is to discuss recent pharmacological progress and clinical application of fungal polysaccharides and fucoidan and to dissect the underlying mechanisms. We expect to collect the studies relevant to polysaccharides and jointly bring advanced scientific progress to polysaccharide research.
Contributions for this Research Topic, both in form of Original Research and Review articles, cover all aspects of fungal polysaccharides and fucoidan. Especially, the Issue focuses on biological functions and action mechanisms, e.g. biological and chemical characterization of polysaccharides from fungi as well as fucoidan; development of the novel strategies for increasing pharmacological activity from fungi and marine organisms; identification of novel molecular mechanisms on fungal polysaccharides and fucoidan suppressed various diseases; application strategies of polysaccharides for pharmaceutical delivery.
We welcome Original Research and Reviews focusing on the following subtopics, but not limited to:
1. Biological pharmacological effects of polysaccharides from fungi as well as fucoidan
2. Isolation, chemical, and structural characterization of novel polysaccharides from fungi as well as fucoidan from seaweed.
3. The application of polysaccharides on pharmaceutical delivery
4. The method for increasing the biological activities of polysaccharides from fungi
5. Clinical research of fungal polysaccharides and fucoidan.
Please note: Frontiers in Experimental Pharmacology and Drug Discovery does not accept publication studies carried out with crude extracts or mixtures. Only the use of highly purified, chemically characterized compounds is acceptable. In vivo systemic effects following oral polysaccharide administration cannot be claimed unless validated by analytical assessment of the plasma concentration of the specific polysaccharide or its monosaccharide constituents.