Alcohol remains the most frequently used intoxicant in the world both among the general population and young individuals. Its ease of accessibility has made alcohol extensively used on both personal and social levels. Alcohol consumption can lead to the progression of a spectrum of diseases affecting the function of different organs in alcohol-dependent subjects, leading to a complex disease phenotype and severe outcomes. According to the World Health Organization’s report on the global status of alcohol and health in 2018, alcohol has accounted for nearly 3 million deaths in the previous few years, translating to about 6 deaths every minute worldwide, underlining the need for new molecular interventions aiming to reduce the burden of alcohol-related diseases in humans.
This Research Topic aims to feature emerging technologies in the field of alcohol research, multi-omics integrations, structural biology, biochemistry, biophysics, neuroscience, and translational aspects of studying the effects of excessive alcohol misuse. The goal of this article collection is to cover a comprehensive illustration of the molecular mechanisms of alcohol addiction and alcohol-induced organ damage by using cutting-edge approaches and to identify emerging technologies for the prevention and treatment of alcohol-dependent disorders.
Basic research, translational studies, and reviews are warmly welcome. Specific themes of the Research Topic may include but are not limited to:
• Excessive alcohol consumption induced multi-organ pathology
• Multi-omics approach to study the spectrum disease of alcohol misuse
• Single-cell RNA-sequencing approach to alcohol-related diseases
• Novel biochemical, bioinformatical, and biophysical tools in studying alcohol addiction and excessive alcohol-induced organ damage in vivo, in vitro, or in silico
Alcohol remains the most frequently used intoxicant in the world both among the general population and young individuals. Its ease of accessibility has made alcohol extensively used on both personal and social levels. Alcohol consumption can lead to the progression of a spectrum of diseases affecting the function of different organs in alcohol-dependent subjects, leading to a complex disease phenotype and severe outcomes. According to the World Health Organization’s report on the global status of alcohol and health in 2018, alcohol has accounted for nearly 3 million deaths in the previous few years, translating to about 6 deaths every minute worldwide, underlining the need for new molecular interventions aiming to reduce the burden of alcohol-related diseases in humans.
This Research Topic aims to feature emerging technologies in the field of alcohol research, multi-omics integrations, structural biology, biochemistry, biophysics, neuroscience, and translational aspects of studying the effects of excessive alcohol misuse. The goal of this article collection is to cover a comprehensive illustration of the molecular mechanisms of alcohol addiction and alcohol-induced organ damage by using cutting-edge approaches and to identify emerging technologies for the prevention and treatment of alcohol-dependent disorders.
Basic research, translational studies, and reviews are warmly welcome. Specific themes of the Research Topic may include but are not limited to:
• Excessive alcohol consumption induced multi-organ pathology
• Multi-omics approach to study the spectrum disease of alcohol misuse
• Single-cell RNA-sequencing approach to alcohol-related diseases
• Novel biochemical, bioinformatical, and biophysical tools in studying alcohol addiction and excessive alcohol-induced organ damage in vivo, in vitro, or in silico