Advances in Integrative Medicine for Neurodegenerative Diseases: From Basic Research to Clinical Practice

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About this Research Topic

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Background

Neurodegenerative diseases (NDs) are disorders characterized by progressive loss of neurons and may finally lead to severe impairments even death. NDs are age-dependent disorders, growing evidence suggests that nearly all aged brains exhibit characteristic changes that are associated with neurodegeneration. As the global rapidly aging population, the prevalence of NDs is which have become the most dreaded disease of aged people. Studies report that the expenses of these older patients with NDs exceed the total medical expenses of patients with cancer and cardiovascular diseases.

As for the pathogenesis of NDs, there is still no clear conclusion on this issue. Although some studies suggest that NDs may be related to protein deposition, attempts against the conditions based on the proteinopathy concept have not achieved gratifying results. Currently, there is no cure for these diseases, and existing treatments only manage symptoms or stop the disease from progressing. Therefore, there is an urgent need for more high-quality research on this disease from basic to clinical, in order to stimulate further understanding and ultimately provide new methods for the prevention and treatment of NDs.

The goal of the research topic is to explore the therapeutic effect and mechanism action of integrative medicine of NDs for the improvement of patient healthcare. For integrative medicine (IM), we mainly focus on Chinese herbal medicine, acupuncture and related therapies, other Chinese medicine therapies based on modern clinical medicine.

Submissions from basic, preventive, clinical, and translational research on NDs are welcomed, especially for those related to complementary and alternative medicine, integrative medicine, etc. We have greatly enjoyed reading articles such as original research, clinical trials, case studies, reviews, systematic reviews, that present the advancement in this direction.

Subjects of interest include but are not limited to:

Validating the therapeutic effect of IM for NDs in clinical studies

Experimental evidence to a therapeutic mechanism of IM for NDs

Clinical findings of the history of NDs and research advances.

Evidence evaluation and synthesis of IM for NDs

Keywords: Neurodegenerative diseases, history of neurology, complementary and alternative medicine, integrative medicine, multiple sources of evidence, preclinical and clinical studies.

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