Cancer is a leading cause of death in children and adolescents, especially in developed countries. In addition, pathologies differ greatly between the cancers affecting children and those affecting adults. The diversity in biology, etiology, and molecular aspects of these cancers are a great challenge for physicians, epidemiologists, and researchers in general. There have been tremendous advances in research, but have in many instances focused on specific race/ethnic populations without adequate coverage across different population groups.
Both clinical presentation and molecular aspects of the cancers show differences depending on the region of the world where the study is carried out. Furthermore, these aspects may have different impact on the prognosis of children, often depending on the way in which the health systems are organized and the level of development of the country where the patients are treated.
The widespread availability of molecular tools and reduction in costs make it possible to advance our knowledge through examining diverse populations, as well as within the context of specific regional conditions. The molecular characteristics of cancer in a specific population allow us to make conjectures about its etiology; it also allows us to examine the effect it has on the prognosis of the disease.
The purpose of this Research Topic is to present current epidemiological research, including molecular epidemiologic findings, of cancers in children and adolescents, representing populations from different parts of the world. This may include the molecular characterization of cancers and assessment of its relationship with disease etiology and prognosis, as well as perspectives describing novel proposals for strategies to investigate these pathologies (commentaries, reviews, etc).
We invite all those interested to submit their manuscripts, especially investigators from countries less represented in the scientific literature regarding the epidemiology of cancers in children and adolescents. We invite researchers to submit hypotheses and perspectives that encourage new research groups to join this challenge of understanding, preventing and reducing morbidity and mortality from cancers among children and adolescents.
Suggested sub-themes can include, but are not limited to:
-Cancer's incidence in children.
-Frequency and incidence of genetic rearrangements in cancers
-Risk factors in children's cancer.
-Interaction between background genetic and environmental factors in the risk of developing cancer in children
-Predisposition to cancer in children.
Cancer is a leading cause of death in children and adolescents, especially in developed countries. In addition, pathologies differ greatly between the cancers affecting children and those affecting adults. The diversity in biology, etiology, and molecular aspects of these cancers are a great challenge for physicians, epidemiologists, and researchers in general. There have been tremendous advances in research, but have in many instances focused on specific race/ethnic populations without adequate coverage across different population groups.
Both clinical presentation and molecular aspects of the cancers show differences depending on the region of the world where the study is carried out. Furthermore, these aspects may have different impact on the prognosis of children, often depending on the way in which the health systems are organized and the level of development of the country where the patients are treated.
The widespread availability of molecular tools and reduction in costs make it possible to advance our knowledge through examining diverse populations, as well as within the context of specific regional conditions. The molecular characteristics of cancer in a specific population allow us to make conjectures about its etiology; it also allows us to examine the effect it has on the prognosis of the disease.
The purpose of this Research Topic is to present current epidemiological research, including molecular epidemiologic findings, of cancers in children and adolescents, representing populations from different parts of the world. This may include the molecular characterization of cancers and assessment of its relationship with disease etiology and prognosis, as well as perspectives describing novel proposals for strategies to investigate these pathologies (commentaries, reviews, etc).
We invite all those interested to submit their manuscripts, especially investigators from countries less represented in the scientific literature regarding the epidemiology of cancers in children and adolescents. We invite researchers to submit hypotheses and perspectives that encourage new research groups to join this challenge of understanding, preventing and reducing morbidity and mortality from cancers among children and adolescents.
Suggested sub-themes can include, but are not limited to:
-Cancer's incidence in children.
-Frequency and incidence of genetic rearrangements in cancers
-Risk factors in children's cancer.
-Interaction between background genetic and environmental factors in the risk of developing cancer in children
-Predisposition to cancer in children.
