Our understanding of the mechanisms underlying the development of multifactorial diseases such as diabetes, autism, Alzheimer's disease, and cancer has been greatly advanced. Non-coding RNAs (ncRNAs), generally including microRNAs and long non-coding RNAs, have recently been found to have potential roles in these diseases, and provide new opportunities for developing both specific biomarkers and therapeutic targets. However, the molecular function and regulation of these RNAs still remains challenging. Numerous studies are focusing on this field in order to fully appreciate the role and regulation of these molecules in human medicine and biology.
This Research Topic aims to bring together researchers working on Non-coding RNAs in different complex diseases. It will highlight the characterization, roles, mechanism and mode of action of these RNAs in complex disorders. The topic will also welcome the researches on the potential role of non-coding RNAs in diagnosis, therapy, and prediction of complex diseases. This Research Topic welcomes original research findings, reviews/minireviews, perspectives/opinions, method articles, as well as new insights on this topic.
Our understanding of the mechanisms underlying the development of multifactorial diseases such as diabetes, autism, Alzheimer's disease, and cancer has been greatly advanced. Non-coding RNAs (ncRNAs), generally including microRNAs and long non-coding RNAs, have recently been found to have potential roles in these diseases, and provide new opportunities for developing both specific biomarkers and therapeutic targets. However, the molecular function and regulation of these RNAs still remains challenging. Numerous studies are focusing on this field in order to fully appreciate the role and regulation of these molecules in human medicine and biology.
This Research Topic aims to bring together researchers working on Non-coding RNAs in different complex diseases. It will highlight the characterization, roles, mechanism and mode of action of these RNAs in complex disorders. The topic will also welcome the researches on the potential role of non-coding RNAs in diagnosis, therapy, and prediction of complex diseases. This Research Topic welcomes original research findings, reviews/minireviews, perspectives/opinions, method articles, as well as new insights on this topic.