The most common reproductive cancers occurring in women are Cervical cancer, Ovarian cancer, Uterine cancer, Vaginal cancer, Vulvar cancer, and Breast cancer (occasionally contemplated reproductive cancer). Prostate cancer, testicular cancer, and penile cancer are all cancers of the male reproductive system.
Cancer is one of the most serious diseases that humans face, and it is still one of the leading causes of death worldwide. Reproductive cancer treatments vary depending on the type of cancer and on when it was discovered, among other factors.
Reproductive cancers have different signs and symptoms, different risk factors, different prevention strategies, and also diverse treatments. A geographic variation on the burden of the dreadful disease suggested that genetics, lifestyle, environment and food consumption modulate an individual’s susceptibility to the disease. Chemotherapy, surgery, radiation therapy are used to treat cancer, but there are limitations, and metastasis is challenging.
Natural products have a long history of use as food and remedy in traditional and modern societies, as well as have been used as herbal medicines and sources of novel bioactive compounds. Currently, natural products or herbal medicine are known to cure the imbalance of the human body caused by diverse diseases including diabetes, neurodegenerative disease, and cancer. Natural products represent an extraordinary resource of structural scaffolds with high diversity that can offer promising chemical agents for making prostate cancer less devastating and curable. Natural products showed anti-cancer effects via regulation of cancer-related proteins, epigenetic factors and reactive oxygenase species.
This Research Topic focuses on the use of natural products, traditional medicine, or herbal medicines in reproductive cancers. We welcome the research into the treatment or prevention of female and male reproductive cancers using extracts and natural derivatives for apoptosis, autophagy induction, anti-angiogenesis, anti-metastasis, and anti-resistance.
This Research Topic encourages all scientists working on drug discovery to treat reproductive cancer, encompassing target identification and validation, preclinical and clinical testing. It will publish articles covering a variety of topics pertinent to the pharmacological field. This Topic intends to exchange information in related areas, such as biochemical, molecular, translational and clinical research; natural products, including isolation, synthesis and biosynthesis, characterization, spectroscopic properties, involving biological activities, including experimental pathology such as tissue culture and fermentation, chemistry, biochemistry, biotechnology, pharmacognosy. Mechanisms of action of new drugs under development, pharmacological technologies, cell signalling, transduction pathway analysis, genomics, proteomics, and metabonomic applications for drug action are all recommended. We welcome both solicited and unsolicited review articles. This section does not cover works with plant extracts that do not include phytochemical characterization.
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Important Note: Extracts and functional foods will be considered if at least one active compound has been detected and quantified. Anti-cancer modalities of natural products demonstrated using
in vitro models must be supported in at least two well-authenticated cancer cell lines (ideally originating from distinct organs/tissues).
All the manuscripts submitted to the collection will need to fully comply with the
Four Pillars of Best Practice in Ethnopharmacology (you can freely download the full version
here).
