Currently, a variety of harmful factors, i.e., pesticides, heavy metals, mycotoxins, veterinary drugs, have been widely found in different foods and feeds, posing high potential health risks to humans and animals. It is important to investigate the in vivo kinetics and metabolisms of these harmful factors for revealing their toxicological mechanisms and toxicities. However, the low concentrations of the targets and complex bio-matrices represent great challenges in the in vivo determination of harmful factors.
Researchers all over the world are continuously working for the development of efficient tools for the analysis of harmful factors in vivo, i.e., LC-MS/MS, electrochemical sensor, optical sensors, et al. The main challenges facing this field are how to ensure the analytical methods with the advantages in terms of high sensitivity, selectivity and accuracy, and even achieving real-time monitoring purpose. In addition, the kinetics and biotransformation of some emerging hazards are still unclear and therefore are critical issues to ensure human and animal health.
In this Research Topic, we are looking forward to publishing the recent advances and the state-of-the-art in the field of in vivo determination of harmful factors, including the design and synthesis of novel nanomaterials for sample pretreatment, electrochemical or optical sensors for real-time detection, biotransformation of emerging harmful factors, and the new application of real-time detection approaches, as well as simulation research. We welcome submissions of Original Research, Review, Mini Review, Perspective, and Short Communications on this topic. Manuscripts submitted to this Research Topic must not be published previously or under consideration for publication elsewhere. Research themes may include, but are not limited to:
• Synthesis of novel nanomaterials, which could efficiently remove the impurities and enrich the targeted analytes in bio-matrices
• Electrochemical or optical methodologies for the sensitive, selective, and real-time determination of in vivo harmful factors
• Adsorption, distribution, metabolism, and excretion of the emerging harmful factors
• New application of real-time detection approaches for in vivo harmful factors
• Theoretical calculation and simulation on sensing nanomaterials/sensors
• Theoretical calculation and simulation on in vivo actions for the harmful factors
Currently, a variety of harmful factors, i.e., pesticides, heavy metals, mycotoxins, veterinary drugs, have been widely found in different foods and feeds, posing high potential health risks to humans and animals. It is important to investigate the in vivo kinetics and metabolisms of these harmful factors for revealing their toxicological mechanisms and toxicities. However, the low concentrations of the targets and complex bio-matrices represent great challenges in the in vivo determination of harmful factors.
Researchers all over the world are continuously working for the development of efficient tools for the analysis of harmful factors in vivo, i.e., LC-MS/MS, electrochemical sensor, optical sensors, et al. The main challenges facing this field are how to ensure the analytical methods with the advantages in terms of high sensitivity, selectivity and accuracy, and even achieving real-time monitoring purpose. In addition, the kinetics and biotransformation of some emerging hazards are still unclear and therefore are critical issues to ensure human and animal health.
In this Research Topic, we are looking forward to publishing the recent advances and the state-of-the-art in the field of in vivo determination of harmful factors, including the design and synthesis of novel nanomaterials for sample pretreatment, electrochemical or optical sensors for real-time detection, biotransformation of emerging harmful factors, and the new application of real-time detection approaches, as well as simulation research. We welcome submissions of Original Research, Review, Mini Review, Perspective, and Short Communications on this topic. Manuscripts submitted to this Research Topic must not be published previously or under consideration for publication elsewhere. Research themes may include, but are not limited to:
• Synthesis of novel nanomaterials, which could efficiently remove the impurities and enrich the targeted analytes in bio-matrices
• Electrochemical or optical methodologies for the sensitive, selective, and real-time determination of in vivo harmful factors
• Adsorption, distribution, metabolism, and excretion of the emerging harmful factors
• New application of real-time detection approaches for in vivo harmful factors
• Theoretical calculation and simulation on sensing nanomaterials/sensors
• Theoretical calculation and simulation on in vivo actions for the harmful factors