In March 2020, a pandemic caused by the SARS-CoV-2 virus that produces COVID-19 disease was declared. This coronavirus has caused the death of millions of people due to pulmonary and systemic deterioration. The most vulnerable people have been the elderly or those with comorbidities. It has been estimated that more than 70 million people worldwide have been diagnosed with SARS-CoV-2, including people with neurodegenerative diseases such as Alzheimer's who are most at risk of hospitalization and death.
The pathways that have been proposed for how the virus affects the nervous system is through direct infection of neurons, causing the induction of inflammatory agents generated by systemic inflammation that reach the brain. Therefore, it is important to pay attention to people with a neurodegenerative disease since it seems that the coronavirus potentiates the disease. Effective treatments must be sought for people with neurodegenerative diseases in order to slow down the effects caused by SARS-CoV-2.
The main goal of this Research Topic is to investigate a sector of the population, such as the elderly who may or may not suffer from a neurodegenerative disease such as Parkinson's or Alzheimer's, and who have been infected by SARS-CoV-2, where a neurodegenerative process has begun. If they already suffer from a neurodegenerative disease, an infection by SARS-CoV-2 seems to contribute to a faster the disease progression.
The virus has already begun to be identified as a promoter of neurodegenerative diseases such as Parkinson's disease as well as a cause of neuroinflammatory processes that lead to neuronal damage and could trigger neurodegenerative diseases. The mechanisms of this process that causes neuronal damage are not completely understood, which is why it is necessary to investigate how this virus is capable of damaging neurons and activating microglia.
This Research Topic welcomes manuscripts on the following themes:
1. SARS-CoV-2 infection in the elderly.
2. Neurodegeneration caused by SARS-CoV-2.
3. Neuroinflammatory process in elderly people infected by SARS-CoV-2.
4. SARS-CoV-2 and Alzheimer's disease.
5. SARS-CoV-2 and Parkinson's disease.
6. Drugs that would help in the treatment and prevention of neurodegenerative processes in people with SARS-CoV-2.
In March 2020, a pandemic caused by the SARS-CoV-2 virus that produces COVID-19 disease was declared. This coronavirus has caused the death of millions of people due to pulmonary and systemic deterioration. The most vulnerable people have been the elderly or those with comorbidities. It has been estimated that more than 70 million people worldwide have been diagnosed with SARS-CoV-2, including people with neurodegenerative diseases such as Alzheimer's who are most at risk of hospitalization and death.
The pathways that have been proposed for how the virus affects the nervous system is through direct infection of neurons, causing the induction of inflammatory agents generated by systemic inflammation that reach the brain. Therefore, it is important to pay attention to people with a neurodegenerative disease since it seems that the coronavirus potentiates the disease. Effective treatments must be sought for people with neurodegenerative diseases in order to slow down the effects caused by SARS-CoV-2.
The main goal of this Research Topic is to investigate a sector of the population, such as the elderly who may or may not suffer from a neurodegenerative disease such as Parkinson's or Alzheimer's, and who have been infected by SARS-CoV-2, where a neurodegenerative process has begun. If they already suffer from a neurodegenerative disease, an infection by SARS-CoV-2 seems to contribute to a faster the disease progression.
The virus has already begun to be identified as a promoter of neurodegenerative diseases such as Parkinson's disease as well as a cause of neuroinflammatory processes that lead to neuronal damage and could trigger neurodegenerative diseases. The mechanisms of this process that causes neuronal damage are not completely understood, which is why it is necessary to investigate how this virus is capable of damaging neurons and activating microglia.
This Research Topic welcomes manuscripts on the following themes:
1. SARS-CoV-2 infection in the elderly.
2. Neurodegeneration caused by SARS-CoV-2.
3. Neuroinflammatory process in elderly people infected by SARS-CoV-2.
4. SARS-CoV-2 and Alzheimer's disease.
5. SARS-CoV-2 and Parkinson's disease.
6. Drugs that would help in the treatment and prevention of neurodegenerative processes in people with SARS-CoV-2.
