Precision Medicine in Gastrointestinal Cancers

57.3K

views

215

authors

24

articles

Precision Medicine in Gastrointestinal Cancers

57.3K

views

215

authors

24

articles

Editors

3

City of Hope National Medical Center

Norfilza M Mokhtar

Department of Physiology, Faculty of Medicine, National University of Malaysia

Raja Affendi Raja Ali

National University of Malaysia

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About

Precision medicine is the main emphasis in healthcare after recognizing the importance to integrate the clinical data with the molecular data of a specific disease. The term was first introduced in 2015 in which the Precision Medicine Initiative was initiated with the final aim to provide targeted therapy with high efficacy and less toxicity. Precision medicine plays an increasingly important in gastrointestinal cancers. Gastrointestinal cancers are divided into the upper (esophagus, stomach) and lower part (hepatobiliary and colon) of the gastrointestinal system. We would like to explore the latest era of integrative therapeutic target in gastrointestinal cancers taking into consideration of various aetiologies including genetic and exposome (dietary factors, microbial, hormonal, environmental insults) and their interactions with the host microenvironment.

Precision medicine is not currently been practiced to treat the commonest gastrointestinal cancers in all countries. The collections of the journals on the topic are currently scattered and it is not focus on the exposome as the main etiology.

Scope of the research topic will be the reviews and original articles on the various areas of research related to gastrointestinal cancers.

Note: Manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (clinical cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.

Precision medicine is the main emphasis in healthcare after recognizing the importance to integrate the clinical data with the molecular data of a specific disease. The term was first introduced in 2015 in which the Precision Medicine Initiative was initiated with the final aim to provide targeted therapy with high efficacy and less toxicity. Precision medicine plays an increasingly important in gastrointestinal cancers. Gastrointestinal cancers are divided into the upper (esophagus, stomach) and lower part (hepatobiliary and colon) of the gastrointestinal system. We would like to explore the latest era of integrative therapeutic target in gastrointestinal cancers taking into consideration of various aetiologies including genetic and exposome (dietary factors, microbial, hormonal, environmental insults) and their interactions with the host microenvironment.

Precision medicine is not currently been practiced to treat the commonest gastrointestinal cancers in all countries. The collections of the journals on the topic are currently scattered and it is not focus on the exposome as the main etiology.

Scope of the research topic will be the reviews and original articles on the various areas of research related to gastrointestinal cancers.

Note: Manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (clinical cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.

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Editors

City of Hope National Medical Center

Norfilza M Mokhtar

Department of Physiology, Faculty of Medicine, National University of Malaysia

Raja Affendi Raja Ali

National University of Malaysia

Impact

57,329 Total views

37,980 Article views

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803 Topic views

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Frontiers in Oncology

Gastrointestinal Cancers: Colorectal Cancer, Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

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