Advanced biomaterials, able not only to replace, but also to treat and/or regenerate the missing or diseased bone, are still indispensable and sought-after in the scientific community. Although extensive research has been done in the field of bone tissue engineering, properties of developed materials are still far from the ones of the natural bone tissue. Even the local drug/ion/cell delivering capacities are not able to fully compensate the difference. Moreover, a vast array of illnesses (i.e., osteoporosis, osteoarthritis, cancer) are making it more difficult to find the appropriate bone substitute material characteristics for bone replacement or local treatment. As the frontiers of biomedical engineering are continuously being pushed, it is not enough anymore to only substitute the missing or resectioned part of the bone tissue, but more advanced approach should be carefully designed and chosen. This ensures that the biomaterial will not only have biocompatible, bioactive and osteoconductive properties, but also the ability to interact with surrounding healthy tissue or to limit the infection risk or disease recurrence.
For bone tissue replacement and repair, myriads of metallic, ceramic, polymeric and biological materials have been historically offered. Each class of these biomaterials has a set of properties which makes them attractive for the specific application. Nevertheless, combinations of inorganic/organic biomaterials open new horizons to design the ideal bone substitute with lessening the burden of the disease, reducing the patient recovery period, as well as augmenting the bone tissue regeneration abilities. Furthermore, combinations of these composite biomaterials with small and large biologically active agents would lead not only to appropriate materials for bone replacement but also locally treat and facilitate new bone formation, offering novel solutions in bone tissue engineering.
This Research Topic on Inorganic/Organic Composite Biomaterials for Bone Replacement, Regeneration and Treatment covers novel ideas and concepts for the development and characterization of advanced combinations of inorganic/organic materials (metals/polymers/ceramics/biological materials), as well as their association with biologically active agents, able to repair, replace, regenerate, and treat the bone tissue. This research topic invites the manuscripts on any of above-mentioned subjects, or others covering the recent progress and new developments in the scope of inorganic/organic composites for bone tissue engineering. Full papers and reviews are welcomed.
Advanced biomaterials, able not only to replace, but also to treat and/or regenerate the missing or diseased bone, are still indispensable and sought-after in the scientific community. Although extensive research has been done in the field of bone tissue engineering, properties of developed materials are still far from the ones of the natural bone tissue. Even the local drug/ion/cell delivering capacities are not able to fully compensate the difference. Moreover, a vast array of illnesses (i.e., osteoporosis, osteoarthritis, cancer) are making it more difficult to find the appropriate bone substitute material characteristics for bone replacement or local treatment. As the frontiers of biomedical engineering are continuously being pushed, it is not enough anymore to only substitute the missing or resectioned part of the bone tissue, but more advanced approach should be carefully designed and chosen. This ensures that the biomaterial will not only have biocompatible, bioactive and osteoconductive properties, but also the ability to interact with surrounding healthy tissue or to limit the infection risk or disease recurrence.
For bone tissue replacement and repair, myriads of metallic, ceramic, polymeric and biological materials have been historically offered. Each class of these biomaterials has a set of properties which makes them attractive for the specific application. Nevertheless, combinations of inorganic/organic biomaterials open new horizons to design the ideal bone substitute with lessening the burden of the disease, reducing the patient recovery period, as well as augmenting the bone tissue regeneration abilities. Furthermore, combinations of these composite biomaterials with small and large biologically active agents would lead not only to appropriate materials for bone replacement but also locally treat and facilitate new bone formation, offering novel solutions in bone tissue engineering.
This Research Topic on Inorganic/Organic Composite Biomaterials for Bone Replacement, Regeneration and Treatment covers novel ideas and concepts for the development and characterization of advanced combinations of inorganic/organic materials (metals/polymers/ceramics/biological materials), as well as their association with biologically active agents, able to repair, replace, regenerate, and treat the bone tissue. This research topic invites the manuscripts on any of above-mentioned subjects, or others covering the recent progress and new developments in the scope of inorganic/organic composites for bone tissue engineering. Full papers and reviews are welcomed.