In most infections caused by parasites, to eliminate them the immune system initiates inflammatory responses that can also damage the host. Successful immune response depends on a fine regulation of the cellular and humoral immune responses that efficiently eliminate the parasites, but that allow the generation of protective immunity. Paradoxically, prolonged, and intense immune responses contribute to worsening the disease. The mechanisms involved in host-parasite interactions are highly complex, involving different cells, signal molecules, cytokines, hormones, metabolites, the presence of co-infections, etc. Knowledge of the mechanisms that activate the immune system and how they contribute to pathogenesis is important to develop efficient therapeutic strategies and / or vaccines against parasites.
This special issue aims to publish high-quality contributions, including original research and review papers covering all aspects of immune responses and immune regulation against parasites such as
Innate and adaptive immunity to infection
Cellular and humoral mediated immunity against parasites
Sexual dimorphism in parasitic diseases
Immunological memory
Immune evasion
Relationship between autoimmunity and parasites
Role of cytokines in susceptibility or resistance on parasitic diseases
immunomodulation on parasitic diseases
Signalling in parasitic diseases
Vaccines against pathogens
Immune response in co-infections
Redox Biology and their influence in pathogens
In most infections caused by parasites, to eliminate them the immune system initiates inflammatory responses that can also damage the host. Successful immune response depends on a fine regulation of the cellular and humoral immune responses that efficiently eliminate the parasites, but that allow the generation of protective immunity. Paradoxically, prolonged, and intense immune responses contribute to worsening the disease. The mechanisms involved in host-parasite interactions are highly complex, involving different cells, signal molecules, cytokines, hormones, metabolites, the presence of co-infections, etc. Knowledge of the mechanisms that activate the immune system and how they contribute to pathogenesis is important to develop efficient therapeutic strategies and / or vaccines against parasites.
This special issue aims to publish high-quality contributions, including original research and review papers covering all aspects of immune responses and immune regulation against parasites such as
Innate and adaptive immunity to infection
Cellular and humoral mediated immunity against parasites
Sexual dimorphism in parasitic diseases
Immunological memory
Immune evasion
Relationship between autoimmunity and parasites
Role of cytokines in susceptibility or resistance on parasitic diseases
immunomodulation on parasitic diseases
Signalling in parasitic diseases
Vaccines against pathogens
Immune response in co-infections
Redox Biology and their influence in pathogens