For many oncological resections, the operative management of blood vessels is of high importance. Vascular dissection is common for locally advanced tumors. Tumors with invasion of arteries or veins necessitate resection of these blood vessels, and, depending on the vessel, vascular reconstruction to ensure sufficient end-organ perfusion or venous drainage. Large tissue defects are commonly reconstructed with pedicled or free flaps, the latter of which require microsurgical vascular anastomoses. Making the decision when such techniques should be employed in individual patients requires broad knowledge and expertise of both the oncological characteristics of the underlying disease and of surgical possibilities and limitations.
Higher-level evidence on outcomes of oncological resections employing blood vessel management is limited for some tumor entities, and results from well-conducted clinical studies are urgently needed. The goal of this Research Topic is to publish evidence on all aspects of surgical oncology where blood vessel management is part of the surgical treatment. Examples are portal and superior mesenteric vein as well as arterial reconstruction in pancreatic resections, vascular resections in cholangiocarcinoma, vessel resections during multi-visceral resection of retroperitoneal sarcoma, pedicled or free flaps to cover tissue defects after resection of limb sarcoma, etc. This evidence would enable surgeons, oncologists, and surgical oncologists to make an informed participative decision together with patients regarding their optimal treatment.
Evidence on all aspects of blood vessel management in surgical oncology, including the right indication for such operations and their outcomes, is welcomed. This evidence should comprise both short-term outcomes such as postoperative morbidity and mortality, postoperative functional indicators, and quality of life as well as long-term functional and oncological outcomes. Literature reviews, as well as original articles including meta-analyses, retrospective, and prospective clinical studies, are welcome.
Please note: manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) will not be accepted in any of the sections of Frontiers in Oncology.
For many oncological resections, the operative management of blood vessels is of high importance. Vascular dissection is common for locally advanced tumors. Tumors with invasion of arteries or veins necessitate resection of these blood vessels, and, depending on the vessel, vascular reconstruction to ensure sufficient end-organ perfusion or venous drainage. Large tissue defects are commonly reconstructed with pedicled or free flaps, the latter of which require microsurgical vascular anastomoses. Making the decision when such techniques should be employed in individual patients requires broad knowledge and expertise of both the oncological characteristics of the underlying disease and of surgical possibilities and limitations.
Higher-level evidence on outcomes of oncological resections employing blood vessel management is limited for some tumor entities, and results from well-conducted clinical studies are urgently needed. The goal of this Research Topic is to publish evidence on all aspects of surgical oncology where blood vessel management is part of the surgical treatment. Examples are portal and superior mesenteric vein as well as arterial reconstruction in pancreatic resections, vascular resections in cholangiocarcinoma, vessel resections during multi-visceral resection of retroperitoneal sarcoma, pedicled or free flaps to cover tissue defects after resection of limb sarcoma, etc. This evidence would enable surgeons, oncologists, and surgical oncologists to make an informed participative decision together with patients regarding their optimal treatment.
Evidence on all aspects of blood vessel management in surgical oncology, including the right indication for such operations and their outcomes, is welcomed. This evidence should comprise both short-term outcomes such as postoperative morbidity and mortality, postoperative functional indicators, and quality of life as well as long-term functional and oncological outcomes. Literature reviews, as well as original articles including meta-analyses, retrospective, and prospective clinical studies, are welcome.
Please note: manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) will not be accepted in any of the sections of Frontiers in Oncology.
