Mood disorders, primarily major depression and bipolar disorder, are complex psychiatric illness involving psychosocial, genetic and epigenetics factors. Although significant progress has been made, many patients fail to fully respond to treatment or become chronically ill. Multifactorial etiologies of mood disorders and the lack of a full understanding of the core neurobiology of these conditions contribute to their treatment challenges. Currently available effective approaches range from psychotherapies to psychopharmacology to neuromodulation. The limits and failures of conventional treatments along with the trend of increased morbidity and mortality have endorsed the quest for alternative and new treatments.
Various strategies are used to enhance suboptimal responses to conventional treatments. Recently, there has been interest in exploring off-label augmentation agents and non-pharmacological interventions to improve clinical response and to reduce the risk of relapse and recurrence. The literature shows an increased use of augmentation strategies for the treatment of mood disorders, such as nutraceuticals or other compounds used as add-on therapy. Moreover, there has been a renewed interest in exploring the treatments with psychedelics in experimental psychological setting. Among the new treatment options, emerging neuromodulation approaches have shown great promise for the treatment of patients with incomplete response.
Although significant progress has been made, there is much to be improved regarding the treatment of mood disorders and the global impact of new treatment strategies.
Numerous advances in research have revealed that augmentation strategies may enhance standard medical practice. Identifying new treatment strategies may be of crucial importance for patients, clinicians, and researchers. This Research Topic aims to collect both original research and review articles addressing augmentation strategies for the treatment of mood disorders, as well as new promising treatment findings.
Potential topics include but are not limited to the following:
Augmentation strategies
Non-traditional therapy
Complementary and alternative medicine
Neuromodulation
Clinical intervention and randomized studies in mood disorders
Mood disorders, primarily major depression and bipolar disorder, are complex psychiatric illness involving psychosocial, genetic and epigenetics factors. Although significant progress has been made, many patients fail to fully respond to treatment or become chronically ill. Multifactorial etiologies of mood disorders and the lack of a full understanding of the core neurobiology of these conditions contribute to their treatment challenges. Currently available effective approaches range from psychotherapies to psychopharmacology to neuromodulation. The limits and failures of conventional treatments along with the trend of increased morbidity and mortality have endorsed the quest for alternative and new treatments.
Various strategies are used to enhance suboptimal responses to conventional treatments. Recently, there has been interest in exploring off-label augmentation agents and non-pharmacological interventions to improve clinical response and to reduce the risk of relapse and recurrence. The literature shows an increased use of augmentation strategies for the treatment of mood disorders, such as nutraceuticals or other compounds used as add-on therapy. Moreover, there has been a renewed interest in exploring the treatments with psychedelics in experimental psychological setting. Among the new treatment options, emerging neuromodulation approaches have shown great promise for the treatment of patients with incomplete response.
Although significant progress has been made, there is much to be improved regarding the treatment of mood disorders and the global impact of new treatment strategies.
Numerous advances in research have revealed that augmentation strategies may enhance standard medical practice. Identifying new treatment strategies may be of crucial importance for patients, clinicians, and researchers. This Research Topic aims to collect both original research and review articles addressing augmentation strategies for the treatment of mood disorders, as well as new promising treatment findings.
Potential topics include but are not limited to the following:
Augmentation strategies
Non-traditional therapy
Complementary and alternative medicine
Neuromodulation
Clinical intervention and randomized studies in mood disorders
