Mucosal melanoma, uveal melanoma, and conjunctival melanoma are rare types of melanoma, each one with its own clinical and biological characteristics. The survival for metastatic uveal melanoma patients is very limited due to a lack of effective treatments. No specific clinical trials for conjunctival melanoma are available due to the rarity of this disease. Both uveal and conjunctival melanoma are excluded from clinical studies testing treatment for cutaneous melanoma. These trials have often included mucosal melanoma despite differing features from cutaneous melanoma.
Despite dramatic therapeutic advances made in the cutaneous melanoma field, the often dismal prognosis of patients with non-cutaneous melanoma warrants continued emphasis on laboratory and clinical research efforts in this rare subset of disease. The purpose of this Research Topic is to collect contributions regarding translational and clinical updates of non-cutaneous melanomas. We welcome submissions on, but limited to, the following themes:
• Advances in therapeutic options for non-cutaneous melanomas (mucosal, uveal, conjunctival)
• New insights regarding Translational features for non-cutaneous melanomas (mucosal, uveal conjunctival)
Please note: manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) will not be accepted in any of the sections of Frontiers in Oncology
Mucosal melanoma, uveal melanoma, and conjunctival melanoma are rare types of melanoma, each one with its own clinical and biological characteristics. The survival for metastatic uveal melanoma patients is very limited due to a lack of effective treatments. No specific clinical trials for conjunctival melanoma are available due to the rarity of this disease. Both uveal and conjunctival melanoma are excluded from clinical studies testing treatment for cutaneous melanoma. These trials have often included mucosal melanoma despite differing features from cutaneous melanoma.
Despite dramatic therapeutic advances made in the cutaneous melanoma field, the often dismal prognosis of patients with non-cutaneous melanoma warrants continued emphasis on laboratory and clinical research efforts in this rare subset of disease. The purpose of this Research Topic is to collect contributions regarding translational and clinical updates of non-cutaneous melanomas. We welcome submissions on, but limited to, the following themes:
• Advances in therapeutic options for non-cutaneous melanomas (mucosal, uveal, conjunctival)
• New insights regarding Translational features for non-cutaneous melanomas (mucosal, uveal conjunctival)
Please note: manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) will not be accepted in any of the sections of Frontiers in Oncology