Pediatric diabetes is a clinical challenge involving caregivers, families and patients. The most common form of diabetes is Type 1 Diabetes; it is the most frequent endocrinopathy in pediatric age; but there are other forms of pediatric diabetes (such as Monogenic Diabetes, Type 2 Diabetes, and secondary Diabetes) that are increasing in prevalence and incidence if the diagnosis is well done.
In particular, during the months of the COVID-19 pandemic, a significant increase in the number of new-onset pediatric Type 2 Diabetes has been reported, but the reasons for this increase are unclear. In addition, there is also an increase in diagnoses of monogenic diabetes worldwide and it is believed that this increase is attributable to the improvement of diagnostic procedures and access to genetic investigations.
This research topic aims to investigate some current aspects of the pathogenesis of Type 1 diabetes and at the same time wants to open new perspectives in the diagnostic path of other forms of diabetes. In particular it will develop some aspects of monogenic diabetes and type 2 diabetes.
The main objective is to turn on a light of attention even towards rare forms of diabetes in developmental age. In fact, we believe that the improvement of the diagnostic approach can facilitate a more appropriate therapy and care and, most of all, it can help lighten the burden of care for all children and adolescents with diabetes and their families.
In the project we intend to insert at least 2 original papers on Type 1 Diabetes, which can open new perspectives in 3 research areas that appear of great interest: the immunology of diabetes, the new technologies and MicroRNAs (mi-RNAs) as biomarkers of disease in children at onset of T1D.
In the context of pediatric type 2 diabetes we would like to include reports on the trend in Italy of this pathology during the pandemic period.
Finally, we plan to investigate some aspects of Monogenic Diabetes in a mini-review that can contribute to the understanding of this form of diabetes.
Articles focusing on novel perspectives in each of the disease types in children and adolescents will be accepted in the form of original research and review.
Pediatric diabetes is a clinical challenge involving caregivers, families and patients. The most common form of diabetes is Type 1 Diabetes; it is the most frequent endocrinopathy in pediatric age; but there are other forms of pediatric diabetes (such as Monogenic Diabetes, Type 2 Diabetes, and secondary Diabetes) that are increasing in prevalence and incidence if the diagnosis is well done.
In particular, during the months of the COVID-19 pandemic, a significant increase in the number of new-onset pediatric Type 2 Diabetes has been reported, but the reasons for this increase are unclear. In addition, there is also an increase in diagnoses of monogenic diabetes worldwide and it is believed that this increase is attributable to the improvement of diagnostic procedures and access to genetic investigations.
This research topic aims to investigate some current aspects of the pathogenesis of Type 1 diabetes and at the same time wants to open new perspectives in the diagnostic path of other forms of diabetes. In particular it will develop some aspects of monogenic diabetes and type 2 diabetes.
The main objective is to turn on a light of attention even towards rare forms of diabetes in developmental age. In fact, we believe that the improvement of the diagnostic approach can facilitate a more appropriate therapy and care and, most of all, it can help lighten the burden of care for all children and adolescents with diabetes and their families.
In the project we intend to insert at least 2 original papers on Type 1 Diabetes, which can open new perspectives in 3 research areas that appear of great interest: the immunology of diabetes, the new technologies and MicroRNAs (mi-RNAs) as biomarkers of disease in children at onset of T1D.
In the context of pediatric type 2 diabetes we would like to include reports on the trend in Italy of this pathology during the pandemic period.
Finally, we plan to investigate some aspects of Monogenic Diabetes in a mini-review that can contribute to the understanding of this form of diabetes.
Articles focusing on novel perspectives in each of the disease types in children and adolescents will be accepted in the form of original research and review.