Helicobacter pylori (H. pylori) is a microaerophilic gram-negative bacterium that colonizes the epithelial cells of gastric mucosa tissue. Numerous studies show that H. pylori infection is the major risk factor for peptic ulcer and gastritis, MALT lymphoma and gastric cancer. The International Agency for Research on Cancer (IARC) has classified H. pylori as the first category of biological carcinogens. The Helicobacter pylori infects approximately half of the world’s population and potentially increases the risk of developing diseases. Epidemiological studies indicate that H. pylori infection is closely related to the occurrence of gastric cancer in terms of socioeconomic background and geography. In addition, research demonstrates that antibiotic resistance of H. pylori is the main reason for the failure of H. pylori eradication. Individualized eradication for H. pylori is of great significance in the prevention and treatment of gastric cancer and has been accepted for increasing the ratio of eradication.
This Research Topic focuses on the prevalence, diagnosis, eradication of H. pylori and the related diseases. In detail, the investigation into the current global epidemiological scope and characteristics of H. pylori is one of interests; research progress on the diagnosis methods of H. pylori infection, as well as the treatment strategy of H. pylori infection and the mechanism of drug resistance and the related diseases caused by H. pylori infection are also welcomed. Additionally, H. pylori infection is the major risk factor for peptic ulcer and gastritis, MALT lymphoma and gastric cancer. Studies on the specific mechanism and susceptibility genes between H. pylori infection and the occurrence and development of these related diseases are needed. Furthermore, the construction of precise prevention, early diagnosis, and clinical treatment for gastric cancer are one of our interests.
Potential topics include but are not limited to the following:
• investigation on the current global epidemiological scope and characteristics of H. pylori;
• techniques of H. pylori typing and virulence analysis;
• risk factors of H. pylori infection;
• screening of high-risk population for H. pylori infection and key preventive measure;
• advancement in diagnosis methods of H. pylori infection;
• treatment strategy of H. pylori infection;
• phenotype detection and the mechanism of drug resistance in H. pylori infection;
• Individualized eradication for H. pylori;
• related diseases caused by H. pylori infection and its specific mechanism;
• screening of susceptibility genes for gastric cancer;
• exploration and application of biomarkers for early diagnosis for gastric cancer;
• construction of precise prevention and treatment system for gastric cancer.
Helicobacter pylori (H. pylori) is a microaerophilic gram-negative bacterium that colonizes the epithelial cells of gastric mucosa tissue. Numerous studies show that H. pylori infection is the major risk factor for peptic ulcer and gastritis, MALT lymphoma and gastric cancer. The International Agency for Research on Cancer (IARC) has classified H. pylori as the first category of biological carcinogens. The Helicobacter pylori infects approximately half of the world’s population and potentially increases the risk of developing diseases. Epidemiological studies indicate that H. pylori infection is closely related to the occurrence of gastric cancer in terms of socioeconomic background and geography. In addition, research demonstrates that antibiotic resistance of H. pylori is the main reason for the failure of H. pylori eradication. Individualized eradication for H. pylori is of great significance in the prevention and treatment of gastric cancer and has been accepted for increasing the ratio of eradication.
This Research Topic focuses on the prevalence, diagnosis, eradication of H. pylori and the related diseases. In detail, the investigation into the current global epidemiological scope and characteristics of H. pylori is one of interests; research progress on the diagnosis methods of H. pylori infection, as well as the treatment strategy of H. pylori infection and the mechanism of drug resistance and the related diseases caused by H. pylori infection are also welcomed. Additionally, H. pylori infection is the major risk factor for peptic ulcer and gastritis, MALT lymphoma and gastric cancer. Studies on the specific mechanism and susceptibility genes between H. pylori infection and the occurrence and development of these related diseases are needed. Furthermore, the construction of precise prevention, early diagnosis, and clinical treatment for gastric cancer are one of our interests.
Potential topics include but are not limited to the following:
• investigation on the current global epidemiological scope and characteristics of H. pylori;
• techniques of H. pylori typing and virulence analysis;
• risk factors of H. pylori infection;
• screening of high-risk population for H. pylori infection and key preventive measure;
• advancement in diagnosis methods of H. pylori infection;
• treatment strategy of H. pylori infection;
• phenotype detection and the mechanism of drug resistance in H. pylori infection;
• Individualized eradication for H. pylori;
• related diseases caused by H. pylori infection and its specific mechanism;
• screening of susceptibility genes for gastric cancer;
• exploration and application of biomarkers for early diagnosis for gastric cancer;
• construction of precise prevention and treatment system for gastric cancer.