Pathogenic microorganisms are causative agents of various infectious diseases becoming increasingly serious worldwide. Therefore, for the successful treatment of pathogenic infection, the rapid and accurate detection of multiple pathogenic microorganisms is of great importance in all areas related to health and safety. Caused by pathogenic bacteria or viruses, more than one billion cases and over one million deaths worldwide occur every year, creating a serious public health threat, especially in developing countries.
Although significant signs of progress are currently being made in infectious diseases control, the precise pathogenic mechanism of some pathogenic microorganisms remain unknown. However, traditional pathogenic microorganism detection has limitations, and it is challenging to identify strains in clinical practice accurately. In addition, drug resistance has increased and become a significant concern for public health issues. For example, Staphylococcus aureus is a ubiquitous human pathogenic microorganism that can trigger various infectious diseases. However, the methicillin-resistant Staphylococcus aureus (MRSA) infection rate has increased worldwide, and the clinical anti-infective treatment for MRSA has become more complex. Besides, relatively little is known about the mechanisms of host-microorganism interactions.
Furthermore, the absence of suitable animal models has become an obstacle in studying several infectious diseases, such as dengue research. With the emergence of multiple recurrent infectious diseases, understanding the intricate mechanisms of hosts detecting and combating invading pathogens will significantly benefit developing new strategies and interventions for controlling infectious diseases. Furthermore, surveillance is key to measuring the effectiveness of interventions and benefiting the control of infectious diseases. Applying statistical methods in predicting pathogen replication and pathogenicity, vector monitoring and control, and disease transmission patterns are critical in monitoring, controlling, and responding to outbreaks of infectious diseases.
In this research topic, we aim to provide new insights into the detection and treatment of pathogenic microorganisms in infectious disease control, including new pathogenic mechanisms, drug resistance, new biomarkers regarding bacterial and viral virulence, and to explore factors influencing host-microbial interactions, with a primary focus on pathogen-induced microbial signatures and modulation of the host immune system.
We welcome the submissions of Original Research, Review and Mini-Review encompassing clinical, epidemiological, translational, and basic research focusing on, but not limited to, the following aspects:
• The novel pathogenic mechanism for infectious diseases
• Emerging infectious diseases caused by pathogenic microorganisms such as bacteria, viruses, and fungi
• New methods and technologies for rapid nucleic acid detection of pathogens and new enzymes (polymerase, nickase, recombinase, endonuclease etc.)
• Applications of new probes and new materials in nucleic acids preparation and signal output
• New findings on drug resistance mechanism
• New dynamic mechanisms on host-microorganism interaction
• Assessment of the risk of disease transmission applying a mathematical model
Pathogenic microorganisms are causative agents of various infectious diseases becoming increasingly serious worldwide. Therefore, for the successful treatment of pathogenic infection, the rapid and accurate detection of multiple pathogenic microorganisms is of great importance in all areas related to health and safety. Caused by pathogenic bacteria or viruses, more than one billion cases and over one million deaths worldwide occur every year, creating a serious public health threat, especially in developing countries.
Although significant signs of progress are currently being made in infectious diseases control, the precise pathogenic mechanism of some pathogenic microorganisms remain unknown. However, traditional pathogenic microorganism detection has limitations, and it is challenging to identify strains in clinical practice accurately. In addition, drug resistance has increased and become a significant concern for public health issues. For example, Staphylococcus aureus is a ubiquitous human pathogenic microorganism that can trigger various infectious diseases. However, the methicillin-resistant Staphylococcus aureus (MRSA) infection rate has increased worldwide, and the clinical anti-infective treatment for MRSA has become more complex. Besides, relatively little is known about the mechanisms of host-microorganism interactions.
Furthermore, the absence of suitable animal models has become an obstacle in studying several infectious diseases, such as dengue research. With the emergence of multiple recurrent infectious diseases, understanding the intricate mechanisms of hosts detecting and combating invading pathogens will significantly benefit developing new strategies and interventions for controlling infectious diseases. Furthermore, surveillance is key to measuring the effectiveness of interventions and benefiting the control of infectious diseases. Applying statistical methods in predicting pathogen replication and pathogenicity, vector monitoring and control, and disease transmission patterns are critical in monitoring, controlling, and responding to outbreaks of infectious diseases.
In this research topic, we aim to provide new insights into the detection and treatment of pathogenic microorganisms in infectious disease control, including new pathogenic mechanisms, drug resistance, new biomarkers regarding bacterial and viral virulence, and to explore factors influencing host-microbial interactions, with a primary focus on pathogen-induced microbial signatures and modulation of the host immune system.
We welcome the submissions of Original Research, Review and Mini-Review encompassing clinical, epidemiological, translational, and basic research focusing on, but not limited to, the following aspects:
• The novel pathogenic mechanism for infectious diseases
• Emerging infectious diseases caused by pathogenic microorganisms such as bacteria, viruses, and fungi
• New methods and technologies for rapid nucleic acid detection of pathogens and new enzymes (polymerase, nickase, recombinase, endonuclease etc.)
• Applications of new probes and new materials in nucleic acids preparation and signal output
• New findings on drug resistance mechanism
• New dynamic mechanisms on host-microorganism interaction
• Assessment of the risk of disease transmission applying a mathematical model