Acute pancreatitis is a common gastrointestinal disease that develops into a life-threatening condition with organ failure in about 10-20% of patients. Gallstones are the most common etiology of acute pancreatitis in China, which is often accompanied by biliary infection or shock if not received timely management. Infection of pancreatic necrosis is associated with mortality rates as high as 30%. Therefore, much attention has been given to the management of pancreatic necrosis to the prevention of infection, as well as treatment of suspected or confirmed infection. For example, much debate exists as to the role of antibiotics in the prevention of infected necrosis. It is also difficult to distinguish infected necrosis from these other conditions such as systemic inflammatory response syndrome based on clinical parameters alone.
This Research Topic is focused on the role and management of gallstones in patients with acute pancreatitis, and the epidemiology, prevention, treatment, and prediction of infected necrotizing pancreatitis.
The scope of the Research Topic includes but is not limited to the following listing items:
• Role and management of Gallstones in patients with acute pancreatitis.
• Prevalence and incidence of infected necrotizing pancreatitis.
• Role of early enteral nutrition in severe acute pancreatitis.
• Antimicrobial prophylaxis of infected necrosis.
• Pathophysiology of necrotizing pancreatitis and infected necrosis.
• Diagnosis of infected pancreatic necrosis.
• Predictors for the presence of infected necrosis.
• Microbiological epidemiology and clinical results of infected pancreatic necrosis.
• Antimicrobial management, minimally invasive (including Endoscopic Step-Up), and open surgical approaches for debridement infected necrotizing pancreatitis.
Acute pancreatitis is a common gastrointestinal disease that develops into a life-threatening condition with organ failure in about 10-20% of patients. Gallstones are the most common etiology of acute pancreatitis in China, which is often accompanied by biliary infection or shock if not received timely management. Infection of pancreatic necrosis is associated with mortality rates as high as 30%. Therefore, much attention has been given to the management of pancreatic necrosis to the prevention of infection, as well as treatment of suspected or confirmed infection. For example, much debate exists as to the role of antibiotics in the prevention of infected necrosis. It is also difficult to distinguish infected necrosis from these other conditions such as systemic inflammatory response syndrome based on clinical parameters alone.
This Research Topic is focused on the role and management of gallstones in patients with acute pancreatitis, and the epidemiology, prevention, treatment, and prediction of infected necrotizing pancreatitis.
The scope of the Research Topic includes but is not limited to the following listing items:
• Role and management of Gallstones in patients with acute pancreatitis.
• Prevalence and incidence of infected necrotizing pancreatitis.
• Role of early enteral nutrition in severe acute pancreatitis.
• Antimicrobial prophylaxis of infected necrosis.
• Pathophysiology of necrotizing pancreatitis and infected necrosis.
• Diagnosis of infected pancreatic necrosis.
• Predictors for the presence of infected necrosis.
• Microbiological epidemiology and clinical results of infected pancreatic necrosis.
• Antimicrobial management, minimally invasive (including Endoscopic Step-Up), and open surgical approaches for debridement infected necrotizing pancreatitis.