Host-Pathogen Interactions Interplay and Cancer: Understanding Mechanisms and Beyond

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About this Research Topic

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Background

Cancer is a huge challenge to the scientific community despite global efforts to unravel its mechanistic insights. Several studies identified the important role of multiple microbes in carcinogenesis. A number of cellular interactions between different hosts and pathogens play a key role in deciding the fate of any cell including cancer development. Recent biological investigations explored several such interactions and paved the way to find out management strategies against a variety of cancers. However, current technological advancement is generating huge host-pathogen interaction data which is developing a scope for its further elaboration using recent tools and methods. The analysis of these interactions through tools, such as network biology and related molecular techniques can add to a clear understanding of the mechanisms and their further utilization in the development of cancer preventive and managing modalities.

The role of microbes in cancer is also evident through several recent studies and the study of host-pathogen interactions is greatly aiding in the understanding of microbes-cancer relationship. As the compiled information about such approaches is scarce and only scattered studies are available, this research topic will open thought-provoking space for the scientific community to use these recent approaches for identifying microbes-mediated carcinogenic processes and their further management.

The Research Topic will cover the following topics:
-Host-pathogen interactions and cancer
-Cancer signaling network and microbes
-Host-pathogen interaction network biology and cancer
-Omics based host-pathogen interactions studies and cancer

We welcome submissions related to host-pathogen interactions and their influence on cancer-associated signaling. The Research Topic welcomes, Original Research and Review especially related to host-pathogen interactions inclusively omics, experimental, network, and computational biology studies deciphering the role of microbes in cancer.

Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.

Keywords: Cancer signaling, Carcinogenesis, host-pathogen interactions, pathogens, host-pathogen interaction network

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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