Diabetic ketoacidosis (DKA) is a harmful and potentially life-threatening complication in patients suffering from diabetes. Despite several awareness campaigns, incidences of DKA at diagnosis of type 1 diabetes are still high. For example, the frequency of DKA diagnosis ranges from approximately 15% to 70% in Europe and North America. In recent years, an increasing number of DKA cases have been observed in the event of onset type 2 diabetes in children and adolescents. It has been estimated that 5% to 25% of patients with type 2 diabetes have DKA at the time of diagnosis. Risk factors for DKA in newly diagnosed patients include younger age, delayed diagnosis, lower socioeconomic status, and residence in a country with a low occurrence of type 1 diabetes. Risk factors for DKA in patients with known diabetes include limited access to medical services, and unrecognized interruption of insulin delivery in patients using an insulin pump.
This Research Topic will explore different aspects of diabetic ketoacidosis in the pediatric population with type 1 diabetes. We welcome research on, but not limited to epidemiology, pathogenesis, clinical course, management, mortality, complications, and prevention of recurrent episodes. Manuscripts exploring extremely rare cases of great importance will also be considered.
We would also like to explore the different trends of DKA occurrence during the COVID-19 pandemic. For example, during lockdown phases, self-isolation and social distancing appeared to be related to an increased risk of severe DKA as parents were often reluctant to take their child to the pediatrician or to the hospital.
We welcome manuscript types such as original research, systematic review, review, perspective, clinical trials, and opinion articles.
Diabetic ketoacidosis (DKA) is a harmful and potentially life-threatening complication in patients suffering from diabetes. Despite several awareness campaigns, incidences of DKA at diagnosis of type 1 diabetes are still high. For example, the frequency of DKA diagnosis ranges from approximately 15% to 70% in Europe and North America. In recent years, an increasing number of DKA cases have been observed in the event of onset type 2 diabetes in children and adolescents. It has been estimated that 5% to 25% of patients with type 2 diabetes have DKA at the time of diagnosis. Risk factors for DKA in newly diagnosed patients include younger age, delayed diagnosis, lower socioeconomic status, and residence in a country with a low occurrence of type 1 diabetes. Risk factors for DKA in patients with known diabetes include limited access to medical services, and unrecognized interruption of insulin delivery in patients using an insulin pump.
This Research Topic will explore different aspects of diabetic ketoacidosis in the pediatric population with type 1 diabetes. We welcome research on, but not limited to epidemiology, pathogenesis, clinical course, management, mortality, complications, and prevention of recurrent episodes. Manuscripts exploring extremely rare cases of great importance will also be considered.
We would also like to explore the different trends of DKA occurrence during the COVID-19 pandemic. For example, during lockdown phases, self-isolation and social distancing appeared to be related to an increased risk of severe DKA as parents were often reluctant to take their child to the pediatrician or to the hospital.
We welcome manuscript types such as original research, systematic review, review, perspective, clinical trials, and opinion articles.