Most tumors are heterogeneous, and the process of direct and indirect interactions between the cell-cell and the cell environment is of paramount importance in their development, invasion, and metastasis. The existing experimental models with conventional primary cells or cell lines are not, or only to a limited extent, suitable for the study of these complex systems. The widespread use of 3D cell and tissue culture technologies (organoids, 3D bioprinting) in recent years has opened up new possibilities in the field of both basic- and applied research and clinical applications as well. New approaches have enabled more effective drug development, clinical diagnostics, and the introduction of therapeutic procedures that can also deliver personalized medicine in the fight against cancer.
At present, the use of these new technologies is not widespread in cancer and immunological research, however, given the technological developments of recent years, this will be inevitable in the future. A number of new, till this time unknown information has already been added to the field of science, and it has been proven with these technologies that tumor cells can be sustained in an in vitro environment that has not been possible so far. The current research Topic aims to update and spread scientist and healthcare workers studying the field of cancer research and therapeutic applications with recent advancements in the field of innovative 3D bioprinting and tissue engineering research. A broader description of the procedures used in clinical diagnostics and the sharing of experience so far would be extremely useful for both researchers and healthcare, so that faster and more effective therapeutic procedures can be used in everyday practice.
This Research Topic focuses on 3D bioprinting and organoid technologies used in cancer and immunology research involving preclinical and clinical applications as well. Original Research, Reviews, and Opinions related to the following subjects are particularly welcome:
• 3D bioprinted tumors for basic and applied research in cancer immunity and immunotherapy
• Organoids for preclinical and/or clinical diagnostics
• 3D bioprinted and tissue-engineered products in anti-cancer immunotherapy and drug development
• Patient and tumor-specific 3D systems in immunology research and therapy
Note: Manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (clinical cohort or biological validation in vitro or in vivo) are out of scope for this section.
Most tumors are heterogeneous, and the process of direct and indirect interactions between the cell-cell and the cell environment is of paramount importance in their development, invasion, and metastasis. The existing experimental models with conventional primary cells or cell lines are not, or only to a limited extent, suitable for the study of these complex systems. The widespread use of 3D cell and tissue culture technologies (organoids, 3D bioprinting) in recent years has opened up new possibilities in the field of both basic- and applied research and clinical applications as well. New approaches have enabled more effective drug development, clinical diagnostics, and the introduction of therapeutic procedures that can also deliver personalized medicine in the fight against cancer.
At present, the use of these new technologies is not widespread in cancer and immunological research, however, given the technological developments of recent years, this will be inevitable in the future. A number of new, till this time unknown information has already been added to the field of science, and it has been proven with these technologies that tumor cells can be sustained in an in vitro environment that has not been possible so far. The current research Topic aims to update and spread scientist and healthcare workers studying the field of cancer research and therapeutic applications with recent advancements in the field of innovative 3D bioprinting and tissue engineering research. A broader description of the procedures used in clinical diagnostics and the sharing of experience so far would be extremely useful for both researchers and healthcare, so that faster and more effective therapeutic procedures can be used in everyday practice.
This Research Topic focuses on 3D bioprinting and organoid technologies used in cancer and immunology research involving preclinical and clinical applications as well. Original Research, Reviews, and Opinions related to the following subjects are particularly welcome:
• 3D bioprinted tumors for basic and applied research in cancer immunity and immunotherapy
• Organoids for preclinical and/or clinical diagnostics
• 3D bioprinted and tissue-engineered products in anti-cancer immunotherapy and drug development
• Patient and tumor-specific 3D systems in immunology research and therapy
Note: Manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (clinical cohort or biological validation in vitro or in vivo) are out of scope for this section.
