The nervous system and immune system work together to provide physiological homeostasis and protect against both infection and injury. While the two systems have traditionally been studied independently, a large body of evidence indicates that neuro-immune interaction is essential to host survival and physiological homeostasis. This is evident in the case of inflammatory disorders and autoimmune disease, where neuromodulation has been beneficial in regulating immune responses. The possibility to control molecular mechanisms through precise nervous system manipulation is central to the emerging fields of neuroimmunology and bioelectronic medicine, which have grown significantly in recent years. An increased understanding of how the nervous system and immune system interact has the potential to introduce novel therapies for treating a wide range of disorders involving dysregulated immune responses.
Our goal is to highlight recent advances in the field of neuroimmunology and bioelectronic medicine for controlling or monitoring responses of the immune system. There are exciting advances taking place in the neural regulation of immunity, including novel cell types in the gut-brain axis, mapping of immune-responsive brain regions, and peripheral focused neuromodulation approaches.
Within this section we welcome submissions of original research (preclinical, human, and animal), reviews, clinical studies and perspective pieces. Areas of interest for this Topic include, but are not limited to:
• Understanding neuro--immune interactions in inflammatory disorders
• Role of cholinergic systems (CNS and PNS) in macrophage activation
• Bioelectronic approaches targeting peripheral nerves to regulate inflammation
• Novel neuro-immune targets and biomarkers for inflammatory disorders
• Novel neuro-immune pathways in cardiovascular disease
• Neural approaches to regulate the resolution of inflammation
• Neuro-immune therapies for targeting inflammation in cancer
• Mapping brain areas that respond to immune events
• Peripheral-focused ultrasound and other non-invasive stimulation modalities
The nervous system and immune system work together to provide physiological homeostasis and protect against both infection and injury. While the two systems have traditionally been studied independently, a large body of evidence indicates that neuro-immune interaction is essential to host survival and physiological homeostasis. This is evident in the case of inflammatory disorders and autoimmune disease, where neuromodulation has been beneficial in regulating immune responses. The possibility to control molecular mechanisms through precise nervous system manipulation is central to the emerging fields of neuroimmunology and bioelectronic medicine, which have grown significantly in recent years. An increased understanding of how the nervous system and immune system interact has the potential to introduce novel therapies for treating a wide range of disorders involving dysregulated immune responses.
Our goal is to highlight recent advances in the field of neuroimmunology and bioelectronic medicine for controlling or monitoring responses of the immune system. There are exciting advances taking place in the neural regulation of immunity, including novel cell types in the gut-brain axis, mapping of immune-responsive brain regions, and peripheral focused neuromodulation approaches.
Within this section we welcome submissions of original research (preclinical, human, and animal), reviews, clinical studies and perspective pieces. Areas of interest for this Topic include, but are not limited to:
• Understanding neuro--immune interactions in inflammatory disorders
• Role of cholinergic systems (CNS and PNS) in macrophage activation
• Bioelectronic approaches targeting peripheral nerves to regulate inflammation
• Novel neuro-immune targets and biomarkers for inflammatory disorders
• Novel neuro-immune pathways in cardiovascular disease
• Neural approaches to regulate the resolution of inflammation
• Neuro-immune therapies for targeting inflammation in cancer
• Mapping brain areas that respond to immune events
• Peripheral-focused ultrasound and other non-invasive stimulation modalities
