Parasitic infection causes considerable death and leads to great economic losses. Parasitic infections are responsible for a high degree of morbidity, mortality and socio-economic under-development, particularly in developing countries of Africa and Southeast Asia.
Most antiparasitic drugs currently available were discovered by screening vast numbers of compounds for their effectiveness against parasites in animal models. e.g. quinine, praziquantel, suramin and albendazole. Nevertheless, the need for novel medications is crucial for preventing or combating major parasitic infections globally. For example, various plants, such as pomegranate, garlic, ginger or clove, possess bioactive compounds, alkaloids and flavonoids, which have been widely used for the treatment of several parasitic diseases, such as malaria, trypanosomiasis, leishmaniasis and schistosomiasis.
Through this Research Topic, we aim to provide significant insight into parasite disease treatment. This include novel therapies, drug resistance, new biomarkers and the factors affecting parasite-host interactions, including the vector profile and the regulation of the host immune system induced by the parasite. In addition, manuscripts dealing with nanotechnology as a possible treatment against parasitic infection will be welcomed.
This Topic will welcome the submission of Original Research articles, Reviews and Mini-Reviews focusing on:
• Mechanisms of action of antiparasitic drugs
• Vaccination against parasitic diseases
• Application of green nanotechnology against parasitic diseases
• Molecular regulation and pathways following the application of natural products or nanoparticles: redox imbalance, gene expression and signaling mechanisms during cell injuries during parasitic infection
Parasitic infection causes considerable death and leads to great economic losses. Parasitic infections are responsible for a high degree of morbidity, mortality and socio-economic under-development, particularly in developing countries of Africa and Southeast Asia.
Most antiparasitic drugs currently available were discovered by screening vast numbers of compounds for their effectiveness against parasites in animal models. e.g. quinine, praziquantel, suramin and albendazole. Nevertheless, the need for novel medications is crucial for preventing or combating major parasitic infections globally. For example, various plants, such as pomegranate, garlic, ginger or clove, possess bioactive compounds, alkaloids and flavonoids, which have been widely used for the treatment of several parasitic diseases, such as malaria, trypanosomiasis, leishmaniasis and schistosomiasis.
Through this Research Topic, we aim to provide significant insight into parasite disease treatment. This include novel therapies, drug resistance, new biomarkers and the factors affecting parasite-host interactions, including the vector profile and the regulation of the host immune system induced by the parasite. In addition, manuscripts dealing with nanotechnology as a possible treatment against parasitic infection will be welcomed.
This Topic will welcome the submission of Original Research articles, Reviews and Mini-Reviews focusing on:
• Mechanisms of action of antiparasitic drugs
• Vaccination against parasitic diseases
• Application of green nanotechnology against parasitic diseases
• Molecular regulation and pathways following the application of natural products or nanoparticles: redox imbalance, gene expression and signaling mechanisms during cell injuries during parasitic infection
