It has become clear in the literature that the neutrophils are able to release neutrophil extracellular traps (NETs), which are a sticky web of DNA conjugated with antimicrobial enzymes (such as myeloperoxidase and histones), resulting in the capture and the killing of different pathogens, including several bacteria and viruses. They represent an important strategy to immobilize and kill invading microorganisms. NETs protect against infection, in particular by large pathogens, but they are also implicated in the pathology associated with a growing number of immune-mediated conditions.
The goal of this Research Topic is to advance our understanding of the involvement of neutrophil extracellular traps in immunity responses to infection and gather the latest research around these structures.
The Research Topic welcomes Original Research, Reviews, Mini Reviews and other article types accepted in the journal.
It has become clear in the literature that the neutrophils are able to release neutrophil extracellular traps (NETs), which are a sticky web of DNA conjugated with antimicrobial enzymes (such as myeloperoxidase and histones), resulting in the capture and the killing of different pathogens, including several bacteria and viruses. They represent an important strategy to immobilize and kill invading microorganisms. NETs protect against infection, in particular by large pathogens, but they are also implicated in the pathology associated with a growing number of immune-mediated conditions.
The goal of this Research Topic is to advance our understanding of the involvement of neutrophil extracellular traps in immunity responses to infection and gather the latest research around these structures.
The Research Topic welcomes Original Research, Reviews, Mini Reviews and other article types accepted in the journal.