Exercise is a powerful tool to improve overall health and quality of life, and evidence supports the notion that exercise can reduce the occurrence or severity of cardiac and skeletal muscle dysfunction associated with pathological conditions. In addition to the direct effects of exercise on muscle tissue, the release of muscle exerkines confers paracrine and endocrine-like functions to stimulate multi-systemic effects. Thus, exercise has the potential to be utilized as a therapeutic intervention independent of direct effects of disease conditions on striated muscle.
While the beneficial effects of exercise on muscle quality and strength are widely recognized, there is still hesitation to prescribe exercise as a therapeutic treatment due to a variety of factors including health status, age and morbidity. In addition, further information is needed to understand how exercise training improves cardiac and skeletal muscle health and to help elucidate appropriate exercise prescriptions to provide optimal muscular and muscle-related whole-body adaptations. Further characterization of adaptations to diverse training programs may ultimately enhance clinical exercise prescription and/or provide novel molecular pathways that can be targeted pharmacologically. Therefore, the goal of this Research Topic is to advance our understanding of the effects of exercise on cardiac and skeletal muscle.
The aim of the current Research Topic is to disseminate promising, recent and novel research trends related to cardiac and skeletal muscle responses to exercise. Areas to be covered in this Research Topic may include, but are not limited to:
• Development of innovative exercise paradigms
• Novel signaling pathways related to exercise adaptations
• Molecular changes of cardiac and skeletal muscle in response to exercise
• Application of exercise or exercise mimetics to improve quality of life
• Muscular response to exercise
• Muscle exerkine discovery
Exercise is a powerful tool to improve overall health and quality of life, and evidence supports the notion that exercise can reduce the occurrence or severity of cardiac and skeletal muscle dysfunction associated with pathological conditions. In addition to the direct effects of exercise on muscle tissue, the release of muscle exerkines confers paracrine and endocrine-like functions to stimulate multi-systemic effects. Thus, exercise has the potential to be utilized as a therapeutic intervention independent of direct effects of disease conditions on striated muscle.
While the beneficial effects of exercise on muscle quality and strength are widely recognized, there is still hesitation to prescribe exercise as a therapeutic treatment due to a variety of factors including health status, age and morbidity. In addition, further information is needed to understand how exercise training improves cardiac and skeletal muscle health and to help elucidate appropriate exercise prescriptions to provide optimal muscular and muscle-related whole-body adaptations. Further characterization of adaptations to diverse training programs may ultimately enhance clinical exercise prescription and/or provide novel molecular pathways that can be targeted pharmacologically. Therefore, the goal of this Research Topic is to advance our understanding of the effects of exercise on cardiac and skeletal muscle.
The aim of the current Research Topic is to disseminate promising, recent and novel research trends related to cardiac and skeletal muscle responses to exercise. Areas to be covered in this Research Topic may include, but are not limited to:
• Development of innovative exercise paradigms
• Novel signaling pathways related to exercise adaptations
• Molecular changes of cardiac and skeletal muscle in response to exercise
• Application of exercise or exercise mimetics to improve quality of life
• Muscular response to exercise
• Muscle exerkine discovery