Gout and Hyperuricemia as Metabolic Risk Factors

23.2K

views

25

authors

5

articles

Gout and Hyperuricemia as Metabolic Risk Factors

23.2K

views

25

authors

5

articles

Editors

2

Samsung Medical Center, Sungkyunkwan University School of Medicine

University of Gothenburg

Impact

Cumulative risk of death overall comparing cases and controls stratified by gender.

Original Research

24 February 2022

Incident Gout: Risk of Death and Cause-Specific Mortality in Western Sweden: A Prospective, Controlled Inception Cohort Study

Mats Dehlin

, 1 more and

Lennart TH Jacobsson

15,055 views

15 citations

Article Cover Image

Original Research

14 December 2022

Uric acid and metabolic syndrome: Findings from national health and nutrition examination survey

Rodney G. Bowden

, 1 more and

Luke T. Richardson

4,339 views

10 citations

Article Cover Image

Original Research

14 February 2022

Gout Arthritis During Admission for Decompensated Heart Failure—A Descriptive Analysis of Risk Factors, Treatment and Prognosis

Fabian Ritter

, 3 more and

Michael Osthoff

3,187 views

7 citations

Original Research

18 October 2021

Anti-gout Medications and Risk of Cardiovascular Disease: A Nested Case-Control Study

Tsung-Ju Chuang

, 2 more and

Chih-Jung Yeh

4,815 views

4 citations

Original Research

14 November 2022

Increased risk of incident gout in young men with metabolic syndrome: A nationwide population-based cohort study of 3.5 million men

Yeonghee Eun

, 8 more and

Jaejoon Lee

5,105 views

2 citations

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About

The prevalence of hyperuricemia and gout has been continuously increasing over the past several decades. Hyperuricemia is a risk factor for gout, but it is well known that it is associated with metabolic syndrome and cardiovascular risk. Gout is also associated with increased cardiovascular risk, and treatment of gout may affect cardiovascular risk. Although it is not clear how hyperuricemia and gout are related to metabolic syndrome and cardiovascular disease, insulin resistance, endothelial dysfunction, oxidative stress, and endoplasmic reticulum stress were suggested as possible mechanisms. Now, Gout is not only an inflammatory disease of the joints, but also a metabolic disease.

This Research Topic aims to elucidate the mechanism by which hyperuricemia and gout act as metabolic risk factors, and to explore the effects of gout itself and its treatment on metabolic syndrome and cardiovascular disease.

We encourage the submission of basic, translational, and clinical researches on the association of hyperuricemia, gout with metabolic syndrome or cardiovascular disease. Here, we welcome original research, reviews, opinion pieces, and clinical trials focusing on the following sample topics:

• Epidemiologic studies focusing on association between gout, hyperuricemia and metabolic disease or cardiovascular risk
• Basic, translational researches on the mechanism by which uric acid acts as metabolic risk factors
• Researches on effect of gout diagnosis or treatment on metabolic disease and cardiovascular disease

The prevalence of hyperuricemia and gout has been continuously increasing over the past several decades. Hyperuricemia is a risk factor for gout, but it is well known that it is associated with metabolic syndrome and cardiovascular risk. Gout is also associated with increased cardiovascular risk, and treatment of gout may affect cardiovascular risk. Although it is not clear how hyperuricemia and gout are related to metabolic syndrome and cardiovascular disease, insulin resistance, endothelial dysfunction, oxidative stress, and endoplasmic reticulum stress were suggested as possible mechanisms. Now, Gout is not only an inflammatory disease of the joints, but also a metabolic disease.

This Research Topic aims to elucidate the mechanism by which hyperuricemia and gout act as metabolic risk factors, and to explore the effects of gout itself and its treatment on metabolic syndrome and cardiovascular disease.

We encourage the submission of basic, translational, and clinical researches on the association of hyperuricemia, gout with metabolic syndrome or cardiovascular disease. Here, we welcome original research, reviews, opinion pieces, and clinical trials focusing on the following sample topics:

• Epidemiologic studies focusing on association between gout, hyperuricemia and metabolic disease or cardiovascular risk
• Basic, translational researches on the mechanism by which uric acid acts as metabolic risk factors
• Researches on effect of gout diagnosis or treatment on metabolic disease and cardiovascular disease

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Editors

Samsung Medical Center, Sungkyunkwan University School of Medicine

University of Gothenburg

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23,234 Total views

17,623 Article views

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Frontiers in Medicine

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