This Research Topic is part of the Marine Microbial-Derived Molecules and Their Potential Medical and Cosmetic Applications:
Marine Microbial-Derived Molecules and Their Potential Medical and Cosmetic ApplicationsThe marine environment is a vast, largely unexploited resource for acquiring a multitude of microbial communities with a number of unknown taxonomic groups and novel biosynthetic capabilities. Marine habitats provide unique conditions for microbial growth and secondary metabolite expressions that are not found in terrestrial ecosystems. The co-evolution of many marine macroorganisms, especially invertebrates, with these microorganisms often leads to a very close association or symbiotic relationship between the host organism and specific microbial species driven by natural products. The ocean basin floor is covered in sediments of different types and origins. Marine sediments are considered to be an incredibly rich source of microbial taxonomic diversity, including ‘unculturable’ microbes. 'Unculturable' microbial diversity presents a vast gene pool for biotechnological exploitation. In this context the secondary metabolites produced by the microbial species and their biosynthetic pathways represent a resource in the discovery of novel molecules or enzymes for a wide number of applications especially in the medical and cosmetic field. Sustainable use of these resources is a methodological challenge: new culture techniques in addition to culture-independent methods, such as PCR amplification from microbial community DNA (metagenome) and functional or sequence-based screening of metagenomic DNA libraries are proving useful for the exploitation of 'unculturable' microbes and their novel gene clusters responsible for biosynthetic pathways for new bioactive compounds and enzymes. In recent years, efforts to characterize marine microbial metagenomics and their associated compounds and enzymes have expanded significantly, but given the vastness of the marine environment and the different types of microbial habitats found there, this research is still in its infancy.
This Research Topic will shed light on the importance marine microbial-derived molecules and their potential medical and cosmetic applications. We warmly welcome submissions, including original research papers and reviews, on this topic.
Potential topics include but are not limited to the following:
• Characterization of marine microbes (collectively the single-celled members of the domains bacteria, archaea and eukarya) as potential sources for new metabolites and other associated compounds
• New marine microbial biosynthetic pathways or biosynthesis for secondary metabolites
• The medical and cosmetic applications of microbial-derived molecules
• Metagenomics for new enzyme discovery and industrial biocatalysis
• Emerging methodologies or high throughput assay technologies developed for marine microbial bioactive molecules discovery
Papers are published upon acceptance, regardless of the Research Topic publication date.
Merely descriptive papers without further application of the obtained data will not be accepted.
This Research Topic is part of the Marine Microbial-Derived Molecules and Their Potential Medical and Cosmetic Applications:
Marine Microbial-Derived Molecules and Their Potential Medical and Cosmetic ApplicationsThe marine environment is a vast, largely unexploited resource for acquiring a multitude of microbial communities with a number of unknown taxonomic groups and novel biosynthetic capabilities. Marine habitats provide unique conditions for microbial growth and secondary metabolite expressions that are not found in terrestrial ecosystems. The co-evolution of many marine macroorganisms, especially invertebrates, with these microorganisms often leads to a very close association or symbiotic relationship between the host organism and specific microbial species driven by natural products. The ocean basin floor is covered in sediments of different types and origins. Marine sediments are considered to be an incredibly rich source of microbial taxonomic diversity, including ‘unculturable’ microbes. 'Unculturable' microbial diversity presents a vast gene pool for biotechnological exploitation. In this context the secondary metabolites produced by the microbial species and their biosynthetic pathways represent a resource in the discovery of novel molecules or enzymes for a wide number of applications especially in the medical and cosmetic field. Sustainable use of these resources is a methodological challenge: new culture techniques in addition to culture-independent methods, such as PCR amplification from microbial community DNA (metagenome) and functional or sequence-based screening of metagenomic DNA libraries are proving useful for the exploitation of 'unculturable' microbes and their novel gene clusters responsible for biosynthetic pathways for new bioactive compounds and enzymes. In recent years, efforts to characterize marine microbial metagenomics and their associated compounds and enzymes have expanded significantly, but given the vastness of the marine environment and the different types of microbial habitats found there, this research is still in its infancy.
This Research Topic will shed light on the importance marine microbial-derived molecules and their potential medical and cosmetic applications. We warmly welcome submissions, including original research papers and reviews, on this topic.
Potential topics include but are not limited to the following:
• Characterization of marine microbes (collectively the single-celled members of the domains bacteria, archaea and eukarya) as potential sources for new metabolites and other associated compounds
• New marine microbial biosynthetic pathways or biosynthesis for secondary metabolites
• The medical and cosmetic applications of microbial-derived molecules
• Metagenomics for new enzyme discovery and industrial biocatalysis
• Emerging methodologies or high throughput assay technologies developed for marine microbial bioactive molecules discovery
Papers are published upon acceptance, regardless of the Research Topic publication date.
Merely descriptive papers without further application of the obtained data will not be accepted.