The prevalence of psychiatric disorders is high across countries. Recently, vast studies have documented that it is the comorbidity of these mental disorders, but not the disorders themselves, that are life-threatening issues. Severe or ignored comorbidity has been indicated to lead to a poorer quality of life and a higher risk of death for these patients and their community. Comorbidity of these psychiatric disorders has always contributed to a high incidence of both unnatural deaths (suicide, homicide, or accident) and natural deaths (e.g. sudden cardiac deaths) among this particular population of patients. Although mechanisms for the development of psychiatric disorders have been highly investigated, these disorders' comorbid conditions, such as somnipathy, suicidal/ homicidal behaviors, and somatic diseases (e.g. medications-related cardiometabolic effects) need to be explored further.
The aim of this Research Topic is to investigate the epidemiological characteristics and pathophysiological mechanisms that underline the development of comorbidity in people affected by psychiatric disorders. Through this Research Topic, we aim to summarize the clinical and forensic characteristics and study the state-of-the-art molecular mechanisms that contribute to the emerging comorbidity associated with psychiatric disorders. With this Research Collection, we hope to highlight the importance of newly-developed strategies for the prevention, diagnosis, and treatment of the comorbidity associated with psychiatric disorders.
We will consider Original Research, Reviews, Clinical Trials, and Methods addressing the following topics:
• Prevalence, clinical and forensic characteristics of comorbid conditions in the patients with psychiatric disorders;
• Molecular mechanism of comorbid somatic diseases such as cardiac lesions and metabolic disorders following antipsychotic and/or antidepressant drug uses, and the mechanisms for the development of other comorbid conditions such as somnipathy and homicidal/suicidal behaviors etc.;
• Novel methods for early recognition and diagnosis of psychiatric disorders comorbid conditions (including neuroimaging, electrophysiology, and molecular levels, etc.).
The prevalence of psychiatric disorders is high across countries. Recently, vast studies have documented that it is the comorbidity of these mental disorders, but not the disorders themselves, that are life-threatening issues. Severe or ignored comorbidity has been indicated to lead to a poorer quality of life and a higher risk of death for these patients and their community. Comorbidity of these psychiatric disorders has always contributed to a high incidence of both unnatural deaths (suicide, homicide, or accident) and natural deaths (e.g. sudden cardiac deaths) among this particular population of patients. Although mechanisms for the development of psychiatric disorders have been highly investigated, these disorders' comorbid conditions, such as somnipathy, suicidal/ homicidal behaviors, and somatic diseases (e.g. medications-related cardiometabolic effects) need to be explored further.
The aim of this Research Topic is to investigate the epidemiological characteristics and pathophysiological mechanisms that underline the development of comorbidity in people affected by psychiatric disorders. Through this Research Topic, we aim to summarize the clinical and forensic characteristics and study the state-of-the-art molecular mechanisms that contribute to the emerging comorbidity associated with psychiatric disorders. With this Research Collection, we hope to highlight the importance of newly-developed strategies for the prevention, diagnosis, and treatment of the comorbidity associated with psychiatric disorders.
We will consider Original Research, Reviews, Clinical Trials, and Methods addressing the following topics:
• Prevalence, clinical and forensic characteristics of comorbid conditions in the patients with psychiatric disorders;
• Molecular mechanism of comorbid somatic diseases such as cardiac lesions and metabolic disorders following antipsychotic and/or antidepressant drug uses, and the mechanisms for the development of other comorbid conditions such as somnipathy and homicidal/suicidal behaviors etc.;
• Novel methods for early recognition and diagnosis of psychiatric disorders comorbid conditions (including neuroimaging, electrophysiology, and molecular levels, etc.).