Recent advances in biocatalysis and biotransformation entail a new era in producing chemicals, food, pharmaceuticals, and bioenergy due to their high yields and selectivity under milder and more eco-friendly conditions. With the wide applications of biocatalysts, including enzymes and whole cells, the production process becomes convenient, clean, and highly efficient. The topics related to biocatalysts include enzyme or microorganism discovery, screening, characterization, immobilization, purification, separation, multi-enzyme catalysis, and process optimization.
In recent years, structural analyses from X-ray diffraction and cryo-electron microscopy studies have enabled scientists to deepen their understanding of the relationship between the function and structure of enzymes. Likewise, advances in protein engineering and synthetic biology have accelerated and expanded the applications of biocatalysis and biotransformation. Novel biocatalysts have been continuously developed and applied in both research and industry.
Carbohydrate is the most abundant natural product in the world, and it can be applied in feedstock, energy production, clinic diagnosis and treatment, cosmetics, and the food industry. However, chemical production encounters problems, including side reactions, low yield, and severe environmental pollution because of the complex structure of carbohydrates. Biotransformation of carbohydrates somehow could prevent these drawbacks.
This Research Topic focuses on the biotransformation of carbohydrates with enzymes or microorganisms. The potential topics of interest include, but are not limited to:
• Screening, cloning, and expression of novel enzymes for biotransformation of carbohydrates
• Protein engineering for improving the enzyme performance
• Screening, characterizing, and optimizing novel microorganisms for whole-cell biocatalysis of carbohydrates
• Synthetic biology for microbial flux optimization or microbial redesign
• Enzyme cascade catalysis or scaffold systems for biotransformation of carbohydrates
• Channeling of substrate(s) or intermediate(s) in multi-step biocatalysis or biotransformation of carbohydrates
• Immobilization of enzymes or whole cells for biotransformation of carbohydrates
• Process optimization for multiple-enzyme catalysis or whole-cell catalysis
Recent advances in biocatalysis and biotransformation entail a new era in producing chemicals, food, pharmaceuticals, and bioenergy due to their high yields and selectivity under milder and more eco-friendly conditions. With the wide applications of biocatalysts, including enzymes and whole cells, the production process becomes convenient, clean, and highly efficient. The topics related to biocatalysts include enzyme or microorganism discovery, screening, characterization, immobilization, purification, separation, multi-enzyme catalysis, and process optimization.
In recent years, structural analyses from X-ray diffraction and cryo-electron microscopy studies have enabled scientists to deepen their understanding of the relationship between the function and structure of enzymes. Likewise, advances in protein engineering and synthetic biology have accelerated and expanded the applications of biocatalysis and biotransformation. Novel biocatalysts have been continuously developed and applied in both research and industry.
Carbohydrate is the most abundant natural product in the world, and it can be applied in feedstock, energy production, clinic diagnosis and treatment, cosmetics, and the food industry. However, chemical production encounters problems, including side reactions, low yield, and severe environmental pollution because of the complex structure of carbohydrates. Biotransformation of carbohydrates somehow could prevent these drawbacks.
This Research Topic focuses on the biotransformation of carbohydrates with enzymes or microorganisms. The potential topics of interest include, but are not limited to:
• Screening, cloning, and expression of novel enzymes for biotransformation of carbohydrates
• Protein engineering for improving the enzyme performance
• Screening, characterizing, and optimizing novel microorganisms for whole-cell biocatalysis of carbohydrates
• Synthetic biology for microbial flux optimization or microbial redesign
• Enzyme cascade catalysis or scaffold systems for biotransformation of carbohydrates
• Channeling of substrate(s) or intermediate(s) in multi-step biocatalysis or biotransformation of carbohydrates
• Immobilization of enzymes or whole cells for biotransformation of carbohydrates
• Process optimization for multiple-enzyme catalysis or whole-cell catalysis