Schistosomiasis is a neglected tropical disease that can cause severe pathological damage to humans. This disease is caused mainly by three species including Schistosoma japonicum, Schistosoma mansoni and Schistosoma haematobium. This group of pathogens is endemic worldwide, especially in developing and impoverished areas, and is a major poverty related disease. As a Neglected Tropical Disease, it is targeted for elimination in the United Nations’ Sustainable Development Goals.
Followed by infecting humans or animals, schistosome cercariae migrate to the host portal-mesenteric vein system where the female worms release a large number of eggs that are transported to the liver through portal veins, causing egg granuloma and hepatic fibrosis, that may eventually cause cirrhosis which is the main cause of mortality of schistosomiasis.
The goal of this Research Topic is to advance our understanding of infections caused by these parasites, describing their biology and interactions with hosts and gather insights for new therapeutic strategies.
The Research Topic welcomes Original Research, Reviews, Mini Reviews and other article types accepted in the journal.
Schistosomiasis is a neglected tropical disease that can cause severe pathological damage to humans. This disease is caused mainly by three species including Schistosoma japonicum, Schistosoma mansoni and Schistosoma haematobium. This group of pathogens is endemic worldwide, especially in developing and impoverished areas, and is a major poverty related disease. As a Neglected Tropical Disease, it is targeted for elimination in the United Nations’ Sustainable Development Goals.
Followed by infecting humans or animals, schistosome cercariae migrate to the host portal-mesenteric vein system where the female worms release a large number of eggs that are transported to the liver through portal veins, causing egg granuloma and hepatic fibrosis, that may eventually cause cirrhosis which is the main cause of mortality of schistosomiasis.
The goal of this Research Topic is to advance our understanding of infections caused by these parasites, describing their biology and interactions with hosts and gather insights for new therapeutic strategies.
The Research Topic welcomes Original Research, Reviews, Mini Reviews and other article types accepted in the journal.