The prevalence of intracranial aneurysms (IA) and the risk of rupture remain unclear. A review suggests that the incidence of aneurysm rupture is underestimated in the guideline of the American Heart Association / American Stroke Association (AHA/ASA), which suggests that at least one in 20 to 30 adults is likely to have a unruptured IA aneurysm and that about a quarter of these aneurysms rupture during life. In practice, it is difficult to predict the rupture of an IA. Despite numerous animal studies and clinical trials, the pathogenesis of IA rupture is still unclear. There are many factors affecting rupture and hemorrhage of intracranial aneurysm, such as demography, aneurysm morphology, family history, underlying disease, personal history, etc.
Moreover, a growing number of studies based on numerical simulations of Computational Fluid Dynamics (CFD), Phase-Contrast Magnetic Resonance Imaging (PC -MRI), 4D- flow MRI, or Transcranial Color-Coded Duplex (TCCD) have shown that hemodynamics is essential for understanding the rupture of IA. However, the different techniques predict different risks, comparative studies are relatively scarce, and accuracy needs further verification.
This Research Topic focuses on risk assessment of IA rupture, including different imaging modalities, flow studies, vessel wall imaging, demography, morphological feature and also clinical characteristics of IA patients. We also welcome predictive models of risk factors based on complete clarification of IA factors associated with rupture from various imaging results (CFD, PC -MRI, 4D Flow MRI, TCCD or Machine Learning, etc.). The the article types of this Research Topic can be Original Research, Clinical Trial, Methods, Review, Study Protocol and Systematic Review.
Topics of interest include:
- Hemodynamic studies, morphological evaluation, demography, underlying disease which are associated with the risk assessment of rupture of IA.
- Different vessel imaging and finding of vessel wall imaging for predicting the risk of intracranial aneurysm rupture.
The prevalence of intracranial aneurysms (IA) and the risk of rupture remain unclear. A review suggests that the incidence of aneurysm rupture is underestimated in the guideline of the American Heart Association / American Stroke Association (AHA/ASA), which suggests that at least one in 20 to 30 adults is likely to have a unruptured IA aneurysm and that about a quarter of these aneurysms rupture during life. In practice, it is difficult to predict the rupture of an IA. Despite numerous animal studies and clinical trials, the pathogenesis of IA rupture is still unclear. There are many factors affecting rupture and hemorrhage of intracranial aneurysm, such as demography, aneurysm morphology, family history, underlying disease, personal history, etc.
Moreover, a growing number of studies based on numerical simulations of Computational Fluid Dynamics (CFD), Phase-Contrast Magnetic Resonance Imaging (PC -MRI), 4D- flow MRI, or Transcranial Color-Coded Duplex (TCCD) have shown that hemodynamics is essential for understanding the rupture of IA. However, the different techniques predict different risks, comparative studies are relatively scarce, and accuracy needs further verification.
This Research Topic focuses on risk assessment of IA rupture, including different imaging modalities, flow studies, vessel wall imaging, demography, morphological feature and also clinical characteristics of IA patients. We also welcome predictive models of risk factors based on complete clarification of IA factors associated with rupture from various imaging results (CFD, PC -MRI, 4D Flow MRI, TCCD or Machine Learning, etc.). The the article types of this Research Topic can be Original Research, Clinical Trial, Methods, Review, Study Protocol and Systematic Review.
Topics of interest include:
- Hemodynamic studies, morphological evaluation, demography, underlying disease which are associated with the risk assessment of rupture of IA.
- Different vessel imaging and finding of vessel wall imaging for predicting the risk of intracranial aneurysm rupture.