The Complexity of Lipid Transfer Protein (LTP)-Related Food Allergy

Lipid Transfer Protein (LTP) is a relevant food allergen and for many years was considered an allergy observed mostly in countries within the Mediterranean Basin. However, in recent years, LTP allergy has been described in several other geographical areas, revealing a more widespread distribution. LTP allergy is a complex entity due to the diverse clinical manifestation, the high number of foods potentially involved, and the frequent involvement of cofactors as modulators of the severity of the reactions. Therefore, LTP allergy is a challenge in several aspects, such as diagnosis, treatment and risk stratification. Indeed, it greatly impacts quality of life and nutrition. However, there is still limited evidence regarding most of these topics.

This Research Topic aims to provide further high-quality evidence surrounding several aspects of LTP-induced food allergy, including diagnosis, treatment, mechanisms, impact and risk stratification.

We welcome the submission of Original Research, Mini reviews and Reviews, including but not limited to the following topics:

-Age-related particularities of LTP allergy: children and elderly.
-LTP allergy geographical patterns.
-The Impact of LTP allergy on nutrition.
-LTP allergy natural history.
-Respiration and LTP allergy.
-LTP allergy treatments such as allergenic immunotherapy.
-New/promising diagnostic tools for LTP allergy.
-Animal models for LTP allergy.
-The Nutritional impact of LTP allergy.
-Quality of life of LTP allergic patients.
-Factors modulating severity in LTP allergy.
-Cofactors in LTP allergy.
-LTP-mediated anaphylaxis.