This Research Topic is part of the
Model Organisms in Aging Research series. Other titles in this series are:
•
Model Organisms in Aging Research:Caenorhabditis elegans•
Model Organisms in Aging Research: Rodent ModelsBackgroundThe discovery of longevity pathways in invertebrate model organisms has been pivotal for the explosion of research in the aging field. Model organisms are amenable to both genetic manipulation and environmental interventions that extend lifespan, slow down the appearance of aging biomarkers and rejuvenate tissues. The simplicity of invertebrates allows the development of concepts and technologies that can then be applied to more complex organisms, including humans.
GoalsSuccessful strategies developed in
Drosophila melanogaster have been useful in studying diverse aspects of aging research, such as the impact of genetics. This has led to key insights into the non-linear relationship between metabolic, immune, genetic, behavioral and aging processes. The goal of this Research Topic is to publish research in any of these areas aided by research with the
Drosophila melanogaster.
Scope and information for AuthorsManuscripts submitted to this Research Topic should include or consider the role of
Drosophila melanogaster for aging research. The scope of this Research Topic covers, but is not limited to, the following themes and questions:
• The genetics of aging; insights from Drosophila melanogaster
• Using flies to test anti-aging interventions (this could include diet restriction as one subtopic and drugs as another)
• The impact of
Drosophila melanogaster research on the aging immune system
• The aging fly: mitochondrial and metabolic insights
• Insights from flies into neurological and behavioral aging
• The strengths and limitations of using
Drosophila melanogaster as a model organism for aging research
This Research Topic is part of the
Model Organisms in Aging Research series. Other titles in this series are:
•
Model Organisms in Aging Research:Caenorhabditis elegans•
Model Organisms in Aging Research: Rodent ModelsBackgroundThe discovery of longevity pathways in invertebrate model organisms has been pivotal for the explosion of research in the aging field. Model organisms are amenable to both genetic manipulation and environmental interventions that extend lifespan, slow down the appearance of aging biomarkers and rejuvenate tissues. The simplicity of invertebrates allows the development of concepts and technologies that can then be applied to more complex organisms, including humans.
GoalsSuccessful strategies developed in
Drosophila melanogaster have been useful in studying diverse aspects of aging research, such as the impact of genetics. This has led to key insights into the non-linear relationship between metabolic, immune, genetic, behavioral and aging processes. The goal of this Research Topic is to publish research in any of these areas aided by research with the
Drosophila melanogaster.
Scope and information for AuthorsManuscripts submitted to this Research Topic should include or consider the role of
Drosophila melanogaster for aging research. The scope of this Research Topic covers, but is not limited to, the following themes and questions:
• The genetics of aging; insights from Drosophila melanogaster
• Using flies to test anti-aging interventions (this could include diet restriction as one subtopic and drugs as another)
• The impact of
Drosophila melanogaster research on the aging immune system
• The aging fly: mitochondrial and metabolic insights
• Insights from flies into neurological and behavioral aging
• The strengths and limitations of using
Drosophila melanogaster as a model organism for aging research