Traditional petrochemical-derived polymers have generated a myriad of pollutants and resulted in serious environmental problems. New methods or technologies for the production of materials with polymer-like properties are urgent to be developed. To reduce the dependence on fossil resources, microbes are discovered and successfully used for producing various types of biopolymers most of which possess biodegradability and biocompatibility from renewable materials. Especially with the rapid development of synthetic biology in recent years, some biopolymers such as polyhydroxyalkanoates (PHAs) and polylactic acid (PLA) have been commercialized and their applications have been expanded into high-end fields. As governments around the world have set carbon neutral goals, biopolymers show a brighter application prospect.
The low productivity, poor material properties, and high cost of biopolymers are remained and restrict the popular application. To make the production of biopolymers more competitive, research should focus on improving the efficiency and cost-effectiveness. It is essential to enhance polymer’s synthesis from low-cost carbon sources or even waste materials through metabolic network analysis and regulation, and optimize the fermentation process by harnessing new-type bioreactor or new fermentation mode. To improve the material properties, more attention should be paid to random or block copolymers and composition control strategies. Meanwhile, greater efforts should be put into screening novel bacterial producers with new metabolic pathways for new high performance polymers or higher capacity for biopolymer production. Moreover, the efficient, low-cost biotechnology for polymer building blocks is worthy of attention.
This Research Topic aims to present a series of Original Research and Review articles covering the latest advances and trends in the microbial synthesis of polymers and their monomers. PHAs, PLA, and other polymers or copolymers are included in this topic. Chemicals that can be polymerized into polymers are all in the scope of this topic, such as lactic acid, succinic acid, 1,3-propanediol, glutaric acid, 3-hydroxypronic acid, ethylene glycol, terephthalic acid, isoprene, etc.
This Topic can include:
1, Description of novel microbes as biopolymer producers
2, Metabolic engineering to improve biopolymer productivity or properties
3, Microbial production of building blocks (lactic acid, succinic acid, 1,3-propanediol, glutaric acid, 3-hydroxypronic acid, isoprene and other monomers) for biopolymers
4, Solutions to reduce the overall cost of biopolymer production
Traditional petrochemical-derived polymers have generated a myriad of pollutants and resulted in serious environmental problems. New methods or technologies for the production of materials with polymer-like properties are urgent to be developed. To reduce the dependence on fossil resources, microbes are discovered and successfully used for producing various types of biopolymers most of which possess biodegradability and biocompatibility from renewable materials. Especially with the rapid development of synthetic biology in recent years, some biopolymers such as polyhydroxyalkanoates (PHAs) and polylactic acid (PLA) have been commercialized and their applications have been expanded into high-end fields. As governments around the world have set carbon neutral goals, biopolymers show a brighter application prospect.
The low productivity, poor material properties, and high cost of biopolymers are remained and restrict the popular application. To make the production of biopolymers more competitive, research should focus on improving the efficiency and cost-effectiveness. It is essential to enhance polymer’s synthesis from low-cost carbon sources or even waste materials through metabolic network analysis and regulation, and optimize the fermentation process by harnessing new-type bioreactor or new fermentation mode. To improve the material properties, more attention should be paid to random or block copolymers and composition control strategies. Meanwhile, greater efforts should be put into screening novel bacterial producers with new metabolic pathways for new high performance polymers or higher capacity for biopolymer production. Moreover, the efficient, low-cost biotechnology for polymer building blocks is worthy of attention.
This Research Topic aims to present a series of Original Research and Review articles covering the latest advances and trends in the microbial synthesis of polymers and their monomers. PHAs, PLA, and other polymers or copolymers are included in this topic. Chemicals that can be polymerized into polymers are all in the scope of this topic, such as lactic acid, succinic acid, 1,3-propanediol, glutaric acid, 3-hydroxypronic acid, ethylene glycol, terephthalic acid, isoprene, etc.
This Topic can include:
1, Description of novel microbes as biopolymer producers
2, Metabolic engineering to improve biopolymer productivity or properties
3, Microbial production of building blocks (lactic acid, succinic acid, 1,3-propanediol, glutaric acid, 3-hydroxypronic acid, isoprene and other monomers) for biopolymers
4, Solutions to reduce the overall cost of biopolymer production