Since the earliest stages of civilization humans apply substances to the skin as medicinal agents or cosmetics. One of the most iconic statements about the skin is attributed to the zoologist Desmond Morris, in 1967, which states that “Flawless skin is the most universally desired human feature”. A healthy skin states health and well-being. Skin regeneration is of extreme importance, as it is required upon a skin trauma or cosmetics. Even though cosmetic or dermocosmetic can sometimes be perceived as a frivolous topic, it has a significant impact on physical and mental health. Peptides present in the skin have different mechanisms of action from epidermal or nervous growth factors or neurotransmitters. It is reported that bioactive peptides can indeed stimulate skin structural protein production like collagen, keratin, and elastin. Therefore, there is a growing interest in research regarding bioactive peptides to enhance skin regeneration.
The aim of this Research Topic is to address the research that has been made in recent years regarding the development of new therapies for skin regeneration, particularly based on bioactive peptides. It is fundamental to develop skin models that can further elucidate the mechanism behind the action of these molecules. The skin is the major organ of the human body, it is responsible for protection, among other functions. Its external exposure results in higher susceptibility to trauma and aging due to extrinsic factors, like UV radiation, pollution, and other inducers of free radicals. To achieve this goal, it is necessary to look to natural products and the best approach to obtain bioactive peptides from natural products or even by-products of industry. As an example, it is known that it is possible to obtain bioactive keratin peptides from the waste of poultry industry, chicken feathers, with the ability to influence skin cells. Moreover, it is necessary to develop more complex in vitro models to evaluate the peptides effect on skin regeneration. Even though 3D skin models have been a hot topic for several years, it is still necessary to improve the current knowledge. Three-dimensional bioprinting is a promising strategy for the production of structured scaffolds to comprise a complex vascularized tissue.
This Research Topic aims to address skin regeneration strategies. The specific areas covered should be the following :
1 – Isolation, identification and characterization of bioactive peptides for skin regeneration
2 – Influence of bioactive peptides on different mechanism of skin regeneration
3 – Influence of bioactive peptides on aging
4 – Influence of bioactive peptides on the treatment of chronic wounds
5 – Influence of peptides on the reduction of scaring upon trauma
5 – Development of 3D In vitro skin models
The authors should address these topics in original research papers or extensive reviews. The preference should be original research papers.
Since the earliest stages of civilization humans apply substances to the skin as medicinal agents or cosmetics. One of the most iconic statements about the skin is attributed to the zoologist Desmond Morris, in 1967, which states that “Flawless skin is the most universally desired human feature”. A healthy skin states health and well-being. Skin regeneration is of extreme importance, as it is required upon a skin trauma or cosmetics. Even though cosmetic or dermocosmetic can sometimes be perceived as a frivolous topic, it has a significant impact on physical and mental health. Peptides present in the skin have different mechanisms of action from epidermal or nervous growth factors or neurotransmitters. It is reported that bioactive peptides can indeed stimulate skin structural protein production like collagen, keratin, and elastin. Therefore, there is a growing interest in research regarding bioactive peptides to enhance skin regeneration.
The aim of this Research Topic is to address the research that has been made in recent years regarding the development of new therapies for skin regeneration, particularly based on bioactive peptides. It is fundamental to develop skin models that can further elucidate the mechanism behind the action of these molecules. The skin is the major organ of the human body, it is responsible for protection, among other functions. Its external exposure results in higher susceptibility to trauma and aging due to extrinsic factors, like UV radiation, pollution, and other inducers of free radicals. To achieve this goal, it is necessary to look to natural products and the best approach to obtain bioactive peptides from natural products or even by-products of industry. As an example, it is known that it is possible to obtain bioactive keratin peptides from the waste of poultry industry, chicken feathers, with the ability to influence skin cells. Moreover, it is necessary to develop more complex in vitro models to evaluate the peptides effect on skin regeneration. Even though 3D skin models have been a hot topic for several years, it is still necessary to improve the current knowledge. Three-dimensional bioprinting is a promising strategy for the production of structured scaffolds to comprise a complex vascularized tissue.
This Research Topic aims to address skin regeneration strategies. The specific areas covered should be the following :
1 – Isolation, identification and characterization of bioactive peptides for skin regeneration
2 – Influence of bioactive peptides on different mechanism of skin regeneration
3 – Influence of bioactive peptides on aging
4 – Influence of bioactive peptides on the treatment of chronic wounds
5 – Influence of peptides on the reduction of scaring upon trauma
5 – Development of 3D In vitro skin models
The authors should address these topics in original research papers or extensive reviews. The preference should be original research papers.