Exosomes are membrane enclosed cellular entities that display specific components on their surface and sequester molecules such as nucleic acids to shuttle as cargo intercellularly for communication purposes. Exosome production and transport via, body fluids such as blood, breast milk, etc, influence the physiological and pathological parameters within the system. Their role in intercellular communication and potential to serve as diagnostic markers along with their application for therapeutic purposes are of great interest to researchers. Studies performed on composition, biogenesis, and trafficking of Exosomes provided insight into the marked changes they undergo in the context of different diseases.
This Research Topic aims to shed light on the latest outstanding discoveries pertinent in a wide spectrum of neurosciences by presenting in-depth information on the different aspects of exosomes like composition, biogenesis, and trafficking and the use of exosomes in diagnosis and target specific delivery of therapeutic in neurodegenerative diseases. Exosomes hold promise to pave way for strategic development in the diagnosis and target specific delivery of therapeutic in neurodegenerative diseases.
This Research Topic will welcome contributions on, but not limited to, the following topics:
1. Exosomes composition, biogenesis and their role in facilitating transport of different cargo
2. Exosomes in physiological and pathological states of Neurodegenerative diseases
3. Exosomes in the progression of Neurodegenerative diseases
4. Exosomes based markers in the diagnosis of Neurodegenerative diseases
5. Exosomes in intracellular communication that influence pathologies of Neurodegenerative diseases
6. Therapeutic cargoes, methods of loading, and possible administration routes for therapeutic applications in Neurodegenerative diseases
For previous research in this field please see the Research Topic:
Exosomes: Role in Cell Function, Neurodegeneration and TherapyExosomes are membrane enclosed cellular entities that display specific components on their surface and sequester molecules such as nucleic acids to shuttle as cargo intercellularly for communication purposes. Exosome production and transport via, body fluids such as blood, breast milk, etc, influence the physiological and pathological parameters within the system. Their role in intercellular communication and potential to serve as diagnostic markers along with their application for therapeutic purposes are of great interest to researchers. Studies performed on composition, biogenesis, and trafficking of Exosomes provided insight into the marked changes they undergo in the context of different diseases.
This Research Topic aims to shed light on the latest outstanding discoveries pertinent in a wide spectrum of neurosciences by presenting in-depth information on the different aspects of exosomes like composition, biogenesis, and trafficking and the use of exosomes in diagnosis and target specific delivery of therapeutic in neurodegenerative diseases. Exosomes hold promise to pave way for strategic development in the diagnosis and target specific delivery of therapeutic in neurodegenerative diseases.
This Research Topic will welcome contributions on, but not limited to, the following topics:
1. Exosomes composition, biogenesis and their role in facilitating transport of different cargo
2. Exosomes in physiological and pathological states of Neurodegenerative diseases
3. Exosomes in the progression of Neurodegenerative diseases
4. Exosomes based markers in the diagnosis of Neurodegenerative diseases
5. Exosomes in intracellular communication that influence pathologies of Neurodegenerative diseases
6. Therapeutic cargoes, methods of loading, and possible administration routes for therapeutic applications in Neurodegenerative diseases
For previous research in this field please see the Research Topic:
Exosomes: Role in Cell Function, Neurodegeneration and Therapy