About this Research Topic
We propose to understand the biology of vesicular compartmentalized organelle mediated events as “vesicular biology” regardless of the location inside or outside the cell. Understand the unique vesicular biology of eukaryotic pathogens will help understand their biology and lead to the development of novel therapeutic strategies.
Vesicular biology is a key to understanding eukaryotes. Parasites adapted their environment and evolved unique vesicular systems to achieve survival in every niche such as intracellular environment surrounded by membrane, parasitophorous vacuole, or cytosol, in the host tissue, and gastrointestinal tract. Currently, advances in molecular biology, cell biology, biochemistry, -omics approach, and bioinformatics, enables us to find shared molecular events in morphologically different organelle, vesicles, and compartments. In this Research Topic, we aim to understand the basics of vesicular biology of parasites. It will unveil uniqueness and universality of vesicular biology in eukaryotes and eventually be expected to develop new diagnostics, vaccines and the treatments to overcome infectious diseases linked to parasites.
This Research Topic will highlight any research and review aiming to understand vesicular biology of parasites including vesicle-, organelle-, and membrane traffic- related processes in parasites. We welcome research focusing on basic biology of these processes. We believe understanding of seamless dynamics of vesicular mediated processes inside and outside the cell shed light into novel biology of eukaryotic and expected to provide seeds for novel therapeutic approaches.
Keywords: Extracellular vesicles, Intracellular vesicles, Vesicular biology, Cell communications, Parasite-host interaction, Parasites, Membrane traffic
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