Sex differences can be found in stroke etiology, efficacy and safety of treatments, and complications in the post-stroke period. The prevalence of stroke in women is increasing rapidly, particularly among the elderly, and more stroke-related deaths are expected to occur in women in the future. Women are more likely to suffer thromboembolic events from atrial fibrillation, can show worse outcomes after stroke treatment, and have a higher percentage of post-stroke depression. Vascular risk factors in women can also have different associations with stroke than in men. Moreover, stroke in pregnancy and postpartum is a rare but very serious condition. Ongoing research shows inconsistent results. For example, the percentage of women, especially elderly women, included in randomized trials is low, making it difficult to create reliable evidence.
To ensure a better understanding of sex differences in stroke, it is important to disseminate knowledge and encourage research in this field. In this Research Topic, we aim to present recent advances in stroke epidemiology, vascular risk factors, etiology, prevention, outcomes, and safety and efficacy of treatment in men and women, as well as basic research on sex differences in stroke. We also aim to shed light on special situations, such as stroke in pregnancy and postpartum, and sex differences in cerebral venous thrombosis and subarachnoid hemorrhage.
As a result, areas of interest include, but are not limited to the following:
• Stroke in pregnancy and postpartum (Reviews).
• Recent advances in basic research on sex differences in stroke (Original Research).
• Cerebral venous thrombosis in women and men (Original Research).
• Sex differences in post-stroke outcomes, such as depression (Original Research).
• Efficacy and safety of acute treatment of ischemic stroke (Reviews).
• Sex differences in stroke prevention (Reviews).
• Subarachnoid hemorrhage in men and women (Original Research).
• Social factors in post-stroke rehabilitation (Original Research).
• Cognitive function/status of post-stroke rehabilitation in men and women (Original Research).
• Inclusion of men and women in randomized stroke trials – creating the evidence (Reviews).
• Stroke in young women including hormonal factors (Original Research).
Sex differences can be found in stroke etiology, efficacy and safety of treatments, and complications in the post-stroke period. The prevalence of stroke in women is increasing rapidly, particularly among the elderly, and more stroke-related deaths are expected to occur in women in the future. Women are more likely to suffer thromboembolic events from atrial fibrillation, can show worse outcomes after stroke treatment, and have a higher percentage of post-stroke depression. Vascular risk factors in women can also have different associations with stroke than in men. Moreover, stroke in pregnancy and postpartum is a rare but very serious condition. Ongoing research shows inconsistent results. For example, the percentage of women, especially elderly women, included in randomized trials is low, making it difficult to create reliable evidence.
To ensure a better understanding of sex differences in stroke, it is important to disseminate knowledge and encourage research in this field. In this Research Topic, we aim to present recent advances in stroke epidemiology, vascular risk factors, etiology, prevention, outcomes, and safety and efficacy of treatment in men and women, as well as basic research on sex differences in stroke. We also aim to shed light on special situations, such as stroke in pregnancy and postpartum, and sex differences in cerebral venous thrombosis and subarachnoid hemorrhage.
As a result, areas of interest include, but are not limited to the following:
• Stroke in pregnancy and postpartum (Reviews).
• Recent advances in basic research on sex differences in stroke (Original Research).
• Cerebral venous thrombosis in women and men (Original Research).
• Sex differences in post-stroke outcomes, such as depression (Original Research).
• Efficacy and safety of acute treatment of ischemic stroke (Reviews).
• Sex differences in stroke prevention (Reviews).
• Subarachnoid hemorrhage in men and women (Original Research).
• Social factors in post-stroke rehabilitation (Original Research).
• Cognitive function/status of post-stroke rehabilitation in men and women (Original Research).
• Inclusion of men and women in randomized stroke trials – creating the evidence (Reviews).
• Stroke in young women including hormonal factors (Original Research).
