Chronic diseases continue to globally represent the top cause of death. Although their aetiology is diverse, anthropogens (including factors related to modern lifestyles or behaviours) are considered common risk factors for meta-inflammation and activation of the inflammatory-oxidative cascade involved in the development and progression of many chronic diseases. The interaction of individuals’ genetic background and/or epigenetic changes with exposure to anthropogens and chemicals may represent the early stages of the pathogenesis of chronic diseases such as cancer and cardiovascular diseases, etc. Time-depending variations in anthropogens exposure (particularly during critical exposure windows) can play a key role in their pathophysiology. Since all these elements contribute differently across individuals for the development of chronic diseases, personalized medicine should consider all the responsible factors involved in the development and progression of these diseases in order to optimize their management and treatment. In addition, the identification of the main risk factors associated with meta-inflammation can make a real difference for providing appropriate and disease-tailored health services.
The goal of this Research Topic is to identify new mechanisms involved in the pathogenesis of chronic diseases and to highlight how lifestyle, nutritional and environmental interventions (apart from specific pharmacologic treatments), can influence the prognosis of such diseases. New approach methodologies (NAMs) can serve to identify specific new targets for personalized interventions that should be translated into clinical studies for proving their efficacy and safety.
This Research Topic is aimed to identify the newest research in the field of personalized medicine in chronic diseases including, but not limited to, genomic medicine. Here, we will focus primarily on the following themes:
• Role of meta-inflammation and inflammatory-oxidative cascade in certain chronic diseases and possible preventive strategies
• Nutritional status and nutritional interventions for the prevention and management of chronic diseases
• Nutritional intervention (e.g., use of nutraceuticals) as a complement to the standard pharmacological treatments for chronic diseases
We welcome you to contribute to this collection with Mini-reviews, Reviews, Perspectives, Protocols, General Commentaries, and Original Research Articles on the topic.
Chronic diseases continue to globally represent the top cause of death. Although their aetiology is diverse, anthropogens (including factors related to modern lifestyles or behaviours) are considered common risk factors for meta-inflammation and activation of the inflammatory-oxidative cascade involved in the development and progression of many chronic diseases. The interaction of individuals’ genetic background and/or epigenetic changes with exposure to anthropogens and chemicals may represent the early stages of the pathogenesis of chronic diseases such as cancer and cardiovascular diseases, etc. Time-depending variations in anthropogens exposure (particularly during critical exposure windows) can play a key role in their pathophysiology. Since all these elements contribute differently across individuals for the development of chronic diseases, personalized medicine should consider all the responsible factors involved in the development and progression of these diseases in order to optimize their management and treatment. In addition, the identification of the main risk factors associated with meta-inflammation can make a real difference for providing appropriate and disease-tailored health services.
The goal of this Research Topic is to identify new mechanisms involved in the pathogenesis of chronic diseases and to highlight how lifestyle, nutritional and environmental interventions (apart from specific pharmacologic treatments), can influence the prognosis of such diseases. New approach methodologies (NAMs) can serve to identify specific new targets for personalized interventions that should be translated into clinical studies for proving their efficacy and safety.
This Research Topic is aimed to identify the newest research in the field of personalized medicine in chronic diseases including, but not limited to, genomic medicine. Here, we will focus primarily on the following themes:
• Role of meta-inflammation and inflammatory-oxidative cascade in certain chronic diseases and possible preventive strategies
• Nutritional status and nutritional interventions for the prevention and management of chronic diseases
• Nutritional intervention (e.g., use of nutraceuticals) as a complement to the standard pharmacological treatments for chronic diseases
We welcome you to contribute to this collection with Mini-reviews, Reviews, Perspectives, Protocols, General Commentaries, and Original Research Articles on the topic.